Publication: Different scaling and root planing strategies in Turkish patients with aggressive periodontitis: A randomized controlled clinical trial
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Date
2022-05-01
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Abstract
Objectives The aim of this study was to compare clinical, cytokine and microbiological responses after quadrant-based scaling and root planing (Q-SRP), full-mouth SRP (FM-SRP) and full-mouth disinfection (FMD) in patients with generalized aggressive periodontitis (GAgP), which is currently termed as generalized stage-III and grade-C periodontitis. Methods Forty-two patients with GAgP were randomly assigned into groups as Q-SRP, FM-SRP or FMD with chlorhexidine. Clinical parameters were recorded, and gingival crevicular fluid (GCF) and subgingival plaque samples were collected at baseline, 3 and 6 months after treatment. GCF levels of interleukin (IL)-1 beta and IL-17 were analysed using ELISA. Quantities of six bacterial species were determined using qPCR. Results Clinical parameters improved significantly in all groups at 3 and 6 months (p 6 mm was lower in the FMD than Q-SRP group at 3 and 6 months (p < 0.05). FMD showed significantly higher percentage of pocket closure compared with Q-SRP and FM-SRP at both 3 and 6 months after treatment (p < 0.05). The IL-1 beta levels decreased only in the FMD group (p < 0.05), whereas no changes were found in IL-17 levels in any group. The levels of five out of six bacterial species decreased at 3 and/or 6 months only in the FMD group (p < 0.05). Conclusions The FMD treatment appears to offer superior outcome than Q-SRP and could be the first choice for patients with GAgP.
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Tıp, Sağlık Bilimleri, Diş Hekimliği, Medicine, Health Sciences, Dentistry, DİŞ HEKİMLİĞİ, ORAL CERRAHİ VE TIP, Klinik Tıp, Klinik Tıp (MED), DENTISTRY, ORAL SURGERY & MEDICINE, CLINICAL MEDICINE, Clinical Medicine (MED), Periodontoloji, Ortodonti, Ağız Cerrahisi, Diş Hijyeni, Dişçilik Hizmetleri, Diş Hekimliği (çeşitli), Periodontics, Orthodontics, Oral Surgery, Dental Hygiene, Dental Assisting, Dentistry (miscellaneous), General Dentistry, aggressive periodontitis, bacteria, interleukin-1 beta, interleukin-17, periodontal debridement, FULL-MOUTH DISINFECTION, EARLY-ONSET PERIODONTITIS, PERI-IMPLANT DISEASES, ONE-STAGE, ULTRASONIC DEBRIDEMENT, CREVICULAR FLUID, CHRONIC ADULT, TH17 CELLS, THERAPY, CLASSIFICATION
Citation
Mamaklioglu D., Karched M., KURU L., Kuru B., Asikainen S., DOĞAN B., "Different scaling and root planing strategies in Turkish patients with aggressive periodontitis: A randomized controlled clinical trial.", International journal of dental hygiene, cilt.20, sa.2, ss.347-363, 2022