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Different scaling and root planing strategies in Turkish patients with aggressive periodontitis: A randomized controlled clinical trial

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dc.contributor.authorDOĞAN, BAŞAK
dc.contributor.authorsMamaklioglu D., Karched M., KURU L., Kuru B., Asikainen S., DOĞAN B.
dc.date.accessioned2023-04-03T10:26:41Z
dc.date.available2023-04-03T10:26:41Z
dc.date.issued2022-05-01
dc.description.abstractObjectives The aim of this study was to compare clinical, cytokine and microbiological responses after quadrant-based scaling and root planing (Q-SRP), full-mouth SRP (FM-SRP) and full-mouth disinfection (FMD) in patients with generalized aggressive periodontitis (GAgP), which is currently termed as generalized stage-III and grade-C periodontitis. Methods Forty-two patients with GAgP were randomly assigned into groups as Q-SRP, FM-SRP or FMD with chlorhexidine. Clinical parameters were recorded, and gingival crevicular fluid (GCF) and subgingival plaque samples were collected at baseline, 3 and 6 months after treatment. GCF levels of interleukin (IL)-1 beta and IL-17 were analysed using ELISA. Quantities of six bacterial species were determined using qPCR. Results Clinical parameters improved significantly in all groups at 3 and 6 months (p 6 mm was lower in the FMD than Q-SRP group at 3 and 6 months (p < 0.05). FMD showed significantly higher percentage of pocket closure compared with Q-SRP and FM-SRP at both 3 and 6 months after treatment (p < 0.05). The IL-1 beta levels decreased only in the FMD group (p < 0.05), whereas no changes were found in IL-17 levels in any group. The levels of five out of six bacterial species decreased at 3 and/or 6 months only in the FMD group (p < 0.05). Conclusions The FMD treatment appears to offer superior outcome than Q-SRP and could be the first choice for patients with GAgP.
dc.identifier.citationMamaklioglu D., Karched M., KURU L., Kuru B., Asikainen S., DOĞAN B., "Different scaling and root planing strategies in Turkish patients with aggressive periodontitis: A randomized controlled clinical trial.", International journal of dental hygiene, cilt.20, sa.2, ss.347-363, 2022
dc.identifier.doi10.1111/idh.12592
dc.identifier.endpage363
dc.identifier.issn1601-5029
dc.identifier.issue2
dc.identifier.startpage347
dc.identifier.urihttps://pubmed.ncbi.nlm.nih.gov/35143714/
dc.identifier.urihttps://hdl.handle.net/11424/288093
dc.identifier.volume20
dc.language.isoeng
dc.relation.ispartofInternational journal of dental hygiene
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectTıp
dc.subjectSağlık Bilimleri
dc.subjectDiş Hekimliği
dc.subjectMedicine
dc.subjectHealth Sciences
dc.subjectDentistry
dc.subjectDİŞ HEKİMLİĞİ, ORAL CERRAHİ VE TIP
dc.subjectKlinik Tıp
dc.subjectKlinik Tıp (MED)
dc.subjectDENTISTRY, ORAL SURGERY & MEDICINE
dc.subjectCLINICAL MEDICINE
dc.subjectClinical Medicine (MED)
dc.subjectPeriodontoloji
dc.subjectOrtodonti
dc.subjectAğız Cerrahisi
dc.subjectDiş Hijyeni
dc.subjectDişçilik Hizmetleri
dc.subjectDiş Hekimliği (çeşitli)
dc.subjectPeriodontics
dc.subjectOrthodontics
dc.subjectOral Surgery
dc.subjectDental Hygiene
dc.subjectDental Assisting
dc.subjectDentistry (miscellaneous)
dc.subjectGeneral Dentistry
dc.subjectaggressive periodontitis
dc.subjectbacteria
dc.subjectinterleukin-1 beta
dc.subjectinterleukin-17
dc.subjectperiodontal debridement
dc.subjectFULL-MOUTH DISINFECTION
dc.subjectEARLY-ONSET PERIODONTITIS
dc.subjectPERI-IMPLANT DISEASES
dc.subjectONE-STAGE
dc.subjectULTRASONIC DEBRIDEMENT
dc.subjectCREVICULAR FLUID
dc.subjectCHRONIC ADULT
dc.subjectTH17 CELLS
dc.subjectTHERAPY
dc.subjectCLASSIFICATION
dc.titleDifferent scaling and root planing strategies in Turkish patients with aggressive periodontitis: A randomized controlled clinical trial
dc.typearticle
dspace.entity.typePublication
local.avesis.id4113d06b-b991-4544-a4e0-78dcb32ec8a6
local.indexed.atWOS
local.indexed.atPUBMED
local.indexed.atSCOPUS
relation.isAuthorOfPublicationa2569f78-7a2a-4f98-8cc9-d8b67ae56f6d
relation.isAuthorOfPublication.latestForDiscoverya2569f78-7a2a-4f98-8cc9-d8b67ae56f6d

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