Person: ÇİMŞİT, CANAN
Loading...
Email Address
Birth Date
Research Projects
Organizational Units
Job Title
Last Name
ÇİMŞİT
First Name
CANAN
Name
18 results
Search Results
Now showing 1 - 10 of 18
Publication Open Access Diagnostic performance between RT-PCR and chest CT in outpatients with clinically suspected COVID-19(2023-08-01) TİGEN, ELİF; ERTÜRK ŞENGEL, BUKET; ÇİMŞİT, CANAN; APAYDIN KAYA, MEMNUNE ÇİĞDEM; KORTEN, VOLKAN; TİGEN E., ERTÜRK ŞENGEL B., ÇİMŞİT C., PERK GURUN H., APAYDIN KAYA M. Ç., KORTEN V.Objective: To investigate the diagnostic performance between chest computed tomography (CT) and reverse transcription-polymerase chain reaction (RT-PCR) in outpatients with suspected coronavirus disease 2019 (COVID-19). Patients and Methods: Between March and June 2020, a total of 812 patients with clinically suspected COVID-19 who underwent both chest CT and initial-single RT-PCR on admission to outpatient units were retrospectively enrolled. CT severity-score (CT-SS) was calculated and data were matched with PCR results. Results: Of 812 patients, 54% (439/812) had positive RT-PCR results, and 47% (425/812) had a positive chest CT scan. With RT-PCR results as reference, the sensitivity, specificity, accuracy of chest CT in defining COVID-19 infection were 60%, (95% CI 56-65%, 265/439 patients), 57% (95% CI 52-62%, 213/373), 59% (95% CI 55-62%, 478/812), respectively. Three hundred eighty-seven (47%) patients had no CT findings, 380/812 (46.8%) had mild, 45/812 (5.5%) had moderate, and no patients in the severe group Conclusion: Chest CT did not show high sensitivity for the diagnosis of COVID-19 for outpatients. We suggest RT-PCR should be the primary diagnostic tool. Chest CT might be considered if there is a strong clinical suspicion with repeatedly negative RT-PCR test results, ensuring infection prevention and control measures can be preserved.Publication Open Access Radiation pneumonitis in relation to pulmonary function, dosimetric factors, TGFβ1 expression, and quality of life in breast cancer patients receiving post-operative radiotherapy: a prospective 6-month follow-up study.(2022-12-08) ÇİMŞİT, CANAN; Ozgen Z., Orun O., Atasoy B. M., Mega Tiber P., Akdeniz E., Cimsit C., Eryuksel E., Karakurt S.Purpose To investigate development of radiation pneumonitis (RP) in relation to pulmonary function, dosimetric factors, and transforming growth factor beta-1 (TGFβ1) expression in irradiated breast cancer patients. Methods A total of 49 breast cancer patients who received post-operative radiotherapy (RT) were evaluated in terms of pulmonary function tests (PFTs), quality of life (QoL), development of RP, dosimetric factors, cytokine levels, and lung highresolution computed tomography (HRCT) before and after RT. ROC analysis was performed for performance of dosimetric factors in predicting RP, while frequencies of single nucleotide polymorphisms (SNPs) genotyped for TGFβ1 (rs11466345 and rs1800470) were also evaluated. Results All cases with RP (10.2%) recovered clinically at the end of third post-RT month. PFT and HRCT parameters were similar before and after RT overall, as well as by RP and the radiation feld subgroups. ROC analysis revealed the signifcant role of the ipsilateral V5 (cutof value of 45.9%, p=0.039), V10 (29.4%, p=0.015), V20 (23%, p=0.017), and MLD (1200 cGy, p=0.030) in predicting RP. Higher post-RT TGFβ1 levels (p=0.037) were noted overall and in patients with RP. Patient and control groups were similar in terms of frequencies of SNPs genotyped for TGFβ1 (rs11466345 and rs1800470). EORTC QLQ-C30 and QLQ-BR-23 scores were similar in patients with vs. without RP. Conclusion Our fndings revealed signifcant role of dosimetric factors including MLD, V20 as well as the low dose-volume metrics in predicting the risk of RP among breast cancer patients who received post-operative RT. Implementation of RT, extent of radiation feld or the presence of RP had no signifcant impact on PFTsPublication Metadata only Spinal vasküler malformasyonlar(Akademisyen Kitabevi, 2023-04-01) ÇİMŞİT, CANAN; Çimşit C.Publication Metadata only The novel OMERACT Ultrasound Scoring System for salivary glands changes in patients with Sjögren's syndrome is associated with MRI and salivary flow rates(2023-11-01) MUMCU, GONCA; ÇİMŞİT, CANAN; Inanc N., Jousse-Joulin S., Abacar K., Cimşit C., Cimşit C., D'Agostino M., Naredo E., Hocevar A., Finzel S., Pineda C., et al.Objective To assess the construct validity of the novel Outcome Measures in Rheumatology (OMERACT) ultrasound (US) semiquantitative scoring system for morphological lesions in major salivary glands by comparing it with magnetic resonance imaging (MRI) and unstimulated whole salivary flow rates (U-WSFRs) in patients with primary Sjögren syndrome (pSS). Methods Nine sonographers applied the OMERACT 0-3 grayscale scoring system for parotid (PGs) and submandibular glands (SMGs) in 11 patients with pSS who also had MRIs performed. These were evaluated by 2 radiologists using a semiquantitative 0-3 scoring system for morphological lesions. The agreement between US and MRI and the association between U-WSFRs and imaging structural lesions was determined. A score ≥ 2 for both US and MRI was defined as gland pathology. Results The prevalence of US morphological lesions in 11 patients with a score ≥ 2 was 58% for PGs and 76% for SMGs, and 46% and 41% for PGs and SMGs, respectively, for MRI. The agreement between OMERACT US scores and MRI scores was 73-91% (median 82%) in the right PG and 73-91% (median 91%) in the left PG, 55-91% (median 55%) in the right SMG and 55-82% (median 55%) in the left SMG. When relations between the presence of hyposalivation and an US score ≥ 2 were examined, agreement was 91-100% (median 83%) in both PGs and 55-91% (median 67%) in both SMGs. Conclusion There is moderate to strong agreement between the OMERACT US and MRI scores for major salivary glands in patients with pSS. Similar agreement ratios were observed between the higher OMERACT US scores and presence of hyposalivation.Publication Open Access Radiological quantification of sarcopenic obesity and its role in chronic liver disease severity(2023-04-01) ÇİMŞİT, CANAN; KURŞUN, MELTEM; DEMİRCİOĞLU, ÖZLEM; GÜNDÜZ, FEYZA; DEMİRTAŞ, COŞKUN ÖZER; Çimşit C., Kurşun M., Demircioğlu Ö., Dilber F., Demirtaş C. Ö., Ergenç İ.Publication Metadata only Assessing the construct validity of the novel OMERACT ultrasound scoring system for salivary glands target lesions by comparison with MRI in patients with sjogren's syndrome - An OMERACT ultrasound working group exercise(2020-10-01) ÇİMŞİT, CANAN; ÇİMŞİT, NURİ ÇAGATAY; Inanc N., Jousse-Joulin S., Abacar K., Cimsit C., Cimsit C., D'Agostino M., Naredo E., Hocevar A., Finzel S., Terslev L., et al.Publication Metadata only 692 Akut Pulmoner Tromboemboli (PTE) hastasında pıhtı yükü ile emboliye eşlik edenparankim bulgularının korelasyonu(2015-10-21) ÇİMŞİT, CANAN; ÇİMŞİT, NURİ ÇAGATAY; KUZAN T. Y., ÇİMŞİT C., ONAYGİL C., ÇİMŞİT N. Ç.Publication Metadata only Venöz inme klinik ve radyolojik yaklaşım(Akademisyen Kitabevi, 2023-04-01) ÇİMŞİT, CANAN; Çimşit C.Publication Open Access Radiological comparison of the Wuhan and B.1.1.7 variant COVID-19 infection; are there any differences in chest CT scans(2022-07-01) DEMİRCİOĞLU, ÖZLEM; KOCAKAYA, DERYA; ÇİMŞİT, CANAN; ÜLGER, NURVER; ÇİMŞİT, NURİ ÇAGATAY; DEMİRCİOĞLU Ö., KOCAKAYA D., ÇİMŞİT C., CAN SARINOĞLU R., ÜLGER N., ÇİMŞİT N. Ç.Aim: In September 2020, a variant of the SARS-CoV-2 virus was detected in England and it became the dominant type in most of the countries. The clinical behavior of the B.1.1.7 variant COVID-19 infectionis different from the Wuhan type.So we aimed to investigate whether there are any differences in computed tomography (CT) imaging findings of pneumonia caused by COVID-19 variants. Material and Method: 340 patients who admitted to the emergency departmentwith symptoms of dyspnea and chest pain suspecting COVID-19 pneumonia and pulmonary embolism were included in the study. Oncology (n:12) and pediatric (n:8) patients, patients with negative PCR test (n:56), and patients infected with different variant (n:6) were excluded leaving 258 patients grouped into two (B.1.1.7 and Wuhan type) for evaluation of CT findings such as pleural thickening,pleural and pericardial effusion, consolidation, GGO presence and distribution, upper lobe involvement, pulmonary embolism, tree in bud pattern, centrilobuler nodule, revers halo sign, and hepatosteatosis. Results: A statistically significant difference was obtained between the two groups in terms of pleural thickening (p=0.020), upper lobe involvement (p=0.037), localization of GGO (p=0.001), presence of pleural effusion (p=0.025), embolism (p=0.011) and presence of consolidation (p=0.042). However, no significant difference was found for the development of hepatosteatosis (p=0.520). Conclusion: There aredifferences in radiological findings between B.1.1.7 variant and Wuhan type. In our study atypical radiological findings are more common in B.1.1.7 type. In addition, radiological findings that seen in severe COVID-19 pneumonia are more common in B.1.1.7.Publication Metadata only Evaluation of vaginal vault position with dMRI in woman who had laparoscopic sacrocolpopexy for uterine prolapse(2015-11-19) YOLDEMİR, AHMET TEVFİK; ÇİMŞİT, CANAN; YOLDEMİR A. T., ÇİMŞİT C., GÜÇLÜ M., AKPINAR İ. N.