Person: MİDİ, İPEK
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MİDİ
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İPEK
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Publication Metadata only Hemichorea associated with polycythaemia vera(SPRINGER, 2006) MİDİ, İPEK; Midi, I.; Dib, H.; Koseoglu, M.; Afsar, N.; Gunal, D. I.Chorea is a rare complication of polycythaemia vera. Polycythaemic chorea occurs predominantly in females and usually in generalised form. We present a 66-year-old woman with acute onset hemichorea-ballism with no vascular pathology in the basal ganglia region. A clear relationship was observed between the onset of chorea and worsening of haematological parameters in the patient. After repeated phlebotomies the patient's clinical status was improved. Polycythaemic chorea must be considered, especially in the elderly, as early diagnosis leads to effective treatment and prevention of complications.Publication Metadata only Intractable seizure with hypoglycemia: A mysterious retroperitoneal fibrosarcoma(2022-01-01) MİDİ, İPEK; EKİNCİ, GAZANFER; MİDİ İ., Okay B. B. , Cetin S. Z. , EKİNCİ G.Publication Open Access Epileptic seizures in cerebral venous sinus thrombosis: Subgroup analysis of VENOST study(W B SAUNDERS CO LTD, 2020-05) MİDİ, İPEK; Uluduz, Derya; Midi, Ipek; Duman, Taskin; Yayla, Vildan; Karahan, Ali Yavuz; Afsar, Nazire; Goksu, Eylem Ozaydin; Mengulluoglu, Necdet; Aytac, Emrah; Sungur, Mehmet Ali; Yesilot, Nilufer; Ince, Birsen; Yalin, Osman Ozgur; Oruc, Serdar; Senol, Mehmet Guney; Yilmaz, Arda; Gokce, Mustafa; Demirci, Seden; Kusbeci, Ozge Yilmaz; Uzuner, Gulnur; Caglayan, Hale Zeynep Batur; Acikgoz, Mustafa; Kurucu, Hatice; Ozdag, Fatih; Baybas, Sevim; Ekmekci, Hakan; Cabala, Murat; Yaman, Mehmet; Yurekli, Vedat Ali; Tekeli, Hakan; Genc, Hamit; Utku, Uygar; Sahin, Sevki; Tokuc, Firdevs Ezgi Ucan; Uzuner, Nevzat; Bektas, Hesna; Kablan, Yuksel; Goksel, Basak Karakurum; Milanlioglu, Aysel; Orken, Dilek Necioglu; Aluclu, Ufuk; Colakoglu, Sena; Tufekci, Ahmet; Bakar, Mustafa; Nazliel, Bijen; Tascilar, Nida; Goksan, Baki; Kozak, Hasan Huseyin; Demir, Serkan; Misirli, Cemile Handan; Kucukoglu, Hayriye; Cinar, Nilgun; Domac, Fusun Mayda; Ozturk, Serefnur; Gunes, TaskinPurpose: The aim of this study is to evaluate the presence and prognostic impact of early seizures in cerebral venous sinus thrombosis patients (CVST). Method: VENOST is a retrospective and prospective national multicenter observational study. CVST patients with or without epileptic seizures (ES) were analyzed and compared in terms of demographic and imaging data, causative factors, clinical variables, and prognosis in a total of 1126 patients. Results: The mean age of the patients in the ES group was 39.73 +/- 12.64 and 40.17 +/- 14.02 years in the non-ES group (p > 0.05). Epileptic seizures were more common (76.6 %) in females (p < 0.001). Early ES occurred in 269 of 1126 patients (23.9 %). Epileptic seizures mainly presented in the acute phase (71.4 %) of the disease (p < 0.001). Majority of these (60.5 %) were in the first 24 h of the CVST. The most common neurological signs were focal neurologic deficits (29.9 %) and altered consciousness (31.4 %) in the ES group. Superior sagittal sinus (SSS) and cortical veins (CV) involvement were the most common sites of thrombosis and the mostly related etiology were found puerperium in seizure group (30.3 % vs 13.9 %). Patients with seizures had worse outcome in the first month of the disease (p < 0.001) but these did not have any influence thereafter. Conclusions: In this largest CVST cohort (VENOST) reported female sex, presence of focal neurological deficits and altered consciousness, thrombosis of the SSS and CVs, hemorrhagic infarction were risk factors for ES occurrence in patients with CVST.Publication Metadata only Clinical and Radiological Features in CADASIL and NOTCH3-Negative Patients: A Multicenter Study from Turkey(KARGER, 2014) MİDİ, İPEK; Ince, Birsen; Benbir, Gulcin; Siva, Aksel; Saip, Sabahattin; Utku, Ufuk; Celik, Yahya; Necioglu-Orken, Dilek; Ozturk, Serefnur; Afsar, Nazire; Aktan, Sevinc; Asil, Talip; Bakac, Goksel; Ekmekci, Hakan; Gokce, Mustafa; Krespi, Yakup; Midi, Lpek; Varlibas, Figen; Citci-Yalcinkaya, Beyza; Goksan, Baki; Uluduz, Derya; Uyguner, OyaBackground: The diversity of clinical presentation and neuroimaging findings of CADASIL (cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy) from different regions of the world has not yet been studied in depth. Here we investigated the variability of clinical, radiological and genetic data of 48 patients analyzed for NOTCH3 mutation in Turkey. Methods: Clinical evaluation was made according to a preformed questionnaire. Cranial neuroimaging findings were determined on the basis of T1, T2, FLAIR and proton-density magnetic resonance scans. For genetic analysis, polymerase chain reaction was performed with primers flanking exons 2-6 and 11 of NOTCH3 gene. Results:Twenty-five patients (52.1%) were diagnosed as CADASIL with NOTCH3 mutation, while 23 patients (47.9%) had no mutation (NOTCH3-negative patients). The mean age and age at stroke onset were lower in male CADASIL patients (p < 0.03). A family history of migraine (p = 0.012), stroke (p < 0.001), recurrent strokes (p = 0.020) and dementia (p = 0.012) was more common in CADASIL patients. Temporal pole involvement was more common in CADASIL patients (p = 0.004). Conclusion: It is of clinical importance to identify the heterogeneity of CADASIL from different countries due to a low correlation of clinical and radiological data with respect to NOTCH3 mutation. (C) 2014 S. Karger AG, BaselPublication Metadata only Theory of mind and its relationship with alexithymia and quality of life in patients with psychogenic nonepileptic seizures: Comparisons with generalised epilepsy and healthy controls(W B SAUNDERS CO LTD, 2021) MİDİ, İPEK; Gursoy, Suha Can; Ergun, Serhat; Midi, Ipek; Topcuoglu, VolkanObjective: Psychogenic nonepileptic seizures (PNES) are associated with high alexithymia, social cognition problems and low quality of life (QoL). Theory of Mind (ToM) has been studied in several conditions as a significant predictor of QoL. We aimed to assess the relationship between ToM abilities, alexithymia and subjective QoL in PNES patients and compare with generalised epilepsy (ES) patients and healthy controls. Method: Patients with PNES (n = 28), ES (n = 28) and healthy volunteers (n = 28) were evaluated for alexithymia and quality of life (QoL) with Toronto Alexithymia Scale-20 (TAS-20) and Short Form-36 (SF-36). Reading the Mind in the Eyes test was used for assessment of affective ToM and Hinting Task and Strange Stories tests for cognitive ToM abilities. Results: Analyses revealed lower SF-36 scores and poorer ToM performance in the PNES group compared to healthy group and poorer cognitive ToM performance than ES group. Cognitive ToM performance was inversely correlated with TAS-20 difficulty identifying feelings subscale and physical functioning subscale of SF-36 in the PNES group. Conclusion: These results are consistent with previous research on PNES and other somatoform disorders and suggest that PNES is associated with impaired ToM task performance. ToM task performance might be related to specific aspects of alexithymia and QoL.Publication Metadata only Motor imagery EEG signal classification using image processing technique over GoogLeNet deep learning algorithm for controlling the robot manipulator(ELSEVIER SCI LTD, 2022) AK, AYÇA; Ak, Ayca; Topuz, Vedat; Midi, IpekControlling of a robotic arm using a brain-computer interface (BCI) is one of the most impressive applications. In this study, a novel method for the classification of motor imaging (MI) electroencephalography (EEG) signals are proposed for BCI. EEG signals are divided into three secondary tables, which were converted into spectrogram images. After applying the spectrogram method, the obtained images are divided into folder structures and deep learning is performed. In the deep learning stage, 400 images are obtained for each task as input to the Goo-gLeNet. After the deep learning completed, the presented system has been tested to imagine up, down, left and right movement to control the movement of the robot arm. It is observed that the robot arm performs the desired movement over 90% accuracy.Publication Metadata only Does measurement of the jugular foramen diameter on MRI help to differentiate transverse sinus thrombosis from unilateral transverse sinus hypoplasia?(SPRINGER-VERLAG ITALIA SRL, 2021) MİDİ, İPEK; Gul, Burcu; Samanci, Cesur; Uluduz, Derya Ugurlu; Alis, Deniz; Midi, Ipek; Kocer, Naci; Islak, Civan; Kizilkilic, OsmanBackground and Purpose The transverse sinus (TS) is a frequent location of cerebral venous thrombosis. However, unilateral TS hypoplasia is a frequent variation and radiological imaging pitfall in the diagnosis because it may mimic unilateral TS thrombosis. The purpose of this study is to find a cutoff value for bilateral jugular foramen (JF) diameter ratios on magnetic resonance imaging (MRI) for differentiating TS thrombosis from TS hypoplasia. Materials and Methods We retrospectively reviewed magnetic resonance venography results for 174 patients with reduced unilateral TS caliber resulting from either unilateral thrombosis (80 patients) or unilateral hypoplasia (94 patients). We calculated the ratio by proportioning the diameter of the JF ipsilateral to the TS with caliber reduction to the diameter of the contralateral JF. The Mann-WhitneyUtest was used to compare the ratios between thrombosis and hypoplasia groups, and the cutoff value was calculated by receiver-operating characteristic curve analysis. Results The ratio of bilateral JF diameters was lower in patients with hypoplasia than those with thrombosis (P < .01). The cutoff value to determine the diagnosis of TS hypoplasia with maximum accuracy was 0.638, with a sensitivity of 91.3% and specificity of 64.9%. Conclusion In equivocal cases, calculating the cutoff value by proportioning the diameter of JF ipsilateral to the TS with caliber reduction to the contralateral JF seems to be an efficient, quick, and straightforward method and valuable aid to differentiate TS thrombosis from TS hypoplasia.Publication Open Access Interictal regional polyspikes in noninvasive EEG suggest cortical dysplasia as etiology of focal epilepsies(WILEY, 2008-06) MİDİ, İPEK; Noachtar, Soheyl; Bilgin, Oezguer; Remi, Jan; Chang, Nelly; Midi, Ipek; Vollmar, Christian; Feddersen, BerendPurpose: To evaluate the clinical significance of interictal regional polyspikes in focal epilepsies secondary to cortical dysplasia. Methods: We performed a data search for the term regional polyspikes in the database of our epilepsy-monitoring unit. Patients with generalized epilepsies including Lennox-Gastaut syndrome were excluded. Regional interictal epileptiform discharges were recorded in 513 patients with noninvasive EEG. Results: We identified 29 patients with interictal regional polyspikes and focal epilepsies. Another 484 patients showed regional epileptiform discharges other than polyspikes. The etiology of the epilepsy was significantly more frequently cortical dysplasia in the group of patients with regional polyspikes (35%, 10 of 29 patients) than in the patients with other regional epileptiform discharges (5%, 24 of 484 patients) (p < 0.01). The polyspikes were significantly more frequently localized to the extratemporal (72%; n = 21) than temporal (28%; n = 8) regions (p < 0.01). In contrast, regional epileptiform discharges other than polyspikes were significantly more frequently localized to the temporal lobe (75%; n = 362) than extratemporal regions (25%; n = 122) (p < 0.01). Eight of the 10 patients with focal cortical dysplasia had extratemporal polyspikes. Discussion: Noninvasively recorded regional polyspikes suggest cortical dysplasias as etiology of predominantly extratemporal epilepsies.Publication Metadata only Visual field analysis in patients with Parkinson's disease(ELSEVIER SCI LTD, 2008) MİDİ, İPEK; Yenice, Ozlem; Onal, Sumru; Midi, Ipek; Ozcan, Eda; Temel, Ahmet; I-Gunal, DilekBackground: To evaluate visual field changes in patients with Parkinson's disease. Methods: Standard automated perimetry of 14 patients (28 eyes) with Parkinson's disease (PD) were compared with controls. PD patients with Unified Parkinson's Disease Rating Scale (UPDRS) score below 25 were included in the study. Results: Visual field indices including mean deviation (-4.69 +/- 2.72 vs. -1.71 +/- 1.30, p = 0.0008), pattern standard deviation (3.94 +/- 1.94 vs. 2.30 +/- 0.41, p = 0.001), and corrected pattern standard deviation (3.23 +/- 2.18 vs. 1.20 +/- 0.91, p = 0.003), were significantly worse in patients with PD when compared with the control group. Bilateral glaucoma-like visual field defects were evident in six patients. Conclusion: Parkinson's patients had worse visual field indices suggesting a common insult in the etiopathogenesis of nerve fiber layer damages observed in glaucoma and PD. (c) 2007 Elsevier Ltd. All rights reserved.Publication Metadata only Bilir kişi raporu(2020-09-01) MİDİ, İPEK; AKVARDAR, YILDIZ; İNANICI, MEHMET AKİF; İŞAK, BARIŞ; MİDİ İ., AKVARDAR Y., TOPÇUOĞLU V., İNANICI M. A., İŞAK B.