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YOLDEMİR, AHMET TEVFİK

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YOLDEMİR

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AHMET TEVFİK

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2012 - 201942020 - 20221
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Has files: true × Subject: Klinik Tıp (MED) ×

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Now showing 1 - 5 of 5
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    PublicationOpen Access
    Telemedicine and women's health
    (2022-09-01) YOLDEMİR, AHMET TEVFİK; Yoldemir T.
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    PublicationOpen Access
    The effect of prolonged time for achieving ovarian suppression before starting stimulation on pregnancy rates in ART cycles
    (2013-01-01) YOLDEMİR, AHMET TEVFİK; YOLDEMİR T.
    Amaç: Stimulasyona başlamadan önce ovaryen süpresyonun uzamasının gebelik oranlarına etkisini araştırmak Hastalar ve Yöntem: Üniversite affiliye hastanede yardımcı üreme tetkikleri (assisted reproductive technologies (ART)) tedavileri yapılan 565 hasta retrospektif olarak incelendi. Kadınlar gonadotropin salgılayan hormon (gonadotropin releasing hormone (GnRH)) analogu ile ovaryen süpresyon süresine göre gruplandırıldı. GnRH analog kullanım süresine göre grup A alt 25 persentil içinde, grup B de üst 25 persentil içindeki hastalardan oluşmaktaydı. İmplantasyon ve klinik gebelik oranları karşılaştırıldı. Bulgular: Grup Ada ortalama aspire edilen ve insemine edilen oosit sayısı grup Bdekinden fazla idi. İmplantasyon oranları benzer idi. Klinik gebelik oranları benzer idi. Sonuç: Ovaryen süpresyon için geçen zamanın uzaması ART sikluslarında klinik gebelik oranlarını olumsuz etkilemez.
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    PublicationOpen Access
    Does the FSH/LH ratio in the serum on the third day of the cycle predict ICSI success
    (2012-10-01) YOLDEMİR, AHMET TEVFİK; YOLDEMİR T., ERENUS M.
    Amaç: Siklusun 3.günü normal FSH değeri olan kadınlarda follikül stimule edici hormon (FSH)/luteinize edici hormon (LH) oranının sitoplazma içi sperm enjeksiyonu (ICSI) başarısının öngörülebilirliğini araştırmak. Hastalar ve Yöntem: Uzun protokol ve rekombinant folikül stimüle edici hormon kullanılarak ICSI tedavisi alan ardışık yüz doksan dokuz infertil kadın retrospektif olarak analiz edildi. Grup A, B, C ve D sırasıyla FSH/LH oranları 2 olan kadınlardan oluşturuldu. Transfer başına klinik gebelik ve implantasyon oranları karşılaştırıldı. Bulgular: Transfer başına klinik gebelik ve implantasyon oranları gruplar arasında benzer idi. Sonuç: Siklusun 3.günü FSH/LH oranı ICSI sikluslarında tedavi sonuçlarını normal 3. gün FSH seviyesi olan kadınlarda öngöremez.
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    PublicationOpen Access
    Pregnancy Rates in Older Poor Responders Who Achieve Embryo Transfer in Long Down-Regulated ART Cycles Are Comparable to Those in Younger Poor Responders
    (2012-05-01) YOLDEMİR, AHMET TEVFİK; YOLDEMİR A. T. , Fraser I. S.
    Objective: To determine whether older women with a poor response to follicular stimulation achieve pregnancy results that are comparable to those of younger poor responders. Methods: Two hundred five women undergoing in vitro fertilization treatment at the Fertility Unit in the Royal Prince Alfred Hospital in Sydney, Australia were selected for retrospective cohort analysis. The outcomes in women > 38 years of age with < 5 oocytes retrieved were compared with those in women ≤ 38 years who also had < 5 oocytes retrieved. Clinical and ongoing pregnancy rates were compared. Results: Implantation rates (21.01 ± 0.38 % vs. 12.82 ± 0.27%, P = 0.11) and clinical pregnancy rates (25.71 ± 0.44% vs. 20.21 ± 0.40%, P = 0.41) were similar in the two groups following cleavage stage embryo transfer. The same was true for blastocyst stage embryo transfer (implantation rates 16.67 ± 0.33% vs. 13.89 ± 0.33%, P = 0.80, and clinical pregnancy rates 23.81 ± 0.44% vs. 16.67 ± 0.38%, P = 0.59). Ongoing pregnancies beyond the 12th week of gestation were also comparable between cleavage stage (24.28 ± 0.43% vs. 16.84 ± 0.34%, P = 0.24) and blastocyst stage embryo transfers (23.81 ± 0.44% vs. 11.11 ± 0.32%, P = 0.32). Conclusion: If older poor responders reach the stage of embryo transfer, they can achieve pregnancy rates similar to those of younger poor responders when matched numbers of embryos are transferred.
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    PublicationOpen Access
    The impact of pregnancy rates of using two different cut-off levels for high serum estradiol levels on the day of the hCG injection: Results from the same cohort of patients with long down-regulated ART cycles
    (2013-01-01) YOLDEMİR, AHMET TEVFİK; YOLDEMİR A. T.
    Objective: To determine, from a single cohort of patients whether on the day of the human chorionic gonadotropin (hCG) injection, two different cut-off levels for high serum estradiol (E2) levels affect pregnancy rates in long-down regulated assisted reproductive technology (ART) cycles. Patients and Methods: A retrospective cohort analysis was performed in a University affiliated hospital on 539 women undergoing consecutive in vitro fertilization/intacytoplasmic sperm injection (IVF/ICSI) treatment with long-down regulation and recombinant follicular stimulating hormone (FSH) injections. The cut-off level for high E2 concentration was calculated according to a centile analysis of E2 levels on the day of hCG administration. Women in group 1 were divided into subgroup A with E2 levels from the 25th to 75th centiles (1040-2500pg/ml) and subgroup B with E2 levels from the 75th to 100th centiles (>2500pg/ml), respectively. Women in group 2 were divided into subgroup A with E2 levels from the 10th to 90th centile (650-3100pg/ml) and subgroup B with E2 levels from the 90th to 100th centile (>3100pg/ml), respectively. The clinical pregnancy rates and ongoing pregnancy rates were compared. Results: The clinical pregnancy rates and ongoing pregnancy rates were similar in group 1 and group 2. Conclusion: High serum E2 levels on the day of the hCG injection day either set at 75th (2500pg/ml) or 90th percentiles (3100pg/ml) do not compromise pregnancy rates in cycles downregulated with gonadotropin-releasing hormone (GnRH) analogues. Key words: Gonadotropin-releasing analogue, Human chorionic gonadotropin, Pregnancy, long analogue cycle, Estradiol