Publication:
Comparison of Conventional Pulmonary Rehabilitation and High-Frequency Chest Wall Oscillation In Primary Ciliary Dyskinesia

dc.contributor.authorKARADAĞ, BÜLENT TANER
dc.contributor.authorsGokdemir, Yasemin; Karadag-Saygi, Evrim; Erdem, Ela; Bayindir, Ozun; Ersu, Refika; Karadag, Bulent; Sekban, Nimet; Akyuz, Gulseren; Karakoc, Fazilet
dc.date.accessioned2022-03-13T12:44:56Z
dc.date.available2022-03-13T12:44:56Z
dc.date.issued2014
dc.description.abstractBackgroundEnhancement of mucociliary clearance by pulmonary rehabilitation (PR) is advocated in primary ciliary dyskinesia (PCD). Our primary aim was to compare the efficacy and safety of postural drainage, percussion and vibration [conventional PR (CPR)], and high frequency chest wall oscillation (HFCWO) by studying change in pulmonary function. Our secondary aim was to evaluate patient preferences regarding the two methods. MethodsThis was a controlled randomized crossover study. PCD patients between the ages of 7 and 18 years were assigned to two groups, first group performed airway clearance with CPR at hospital for 5 days and after a 2-day washout period HFCWO was applied to the same group at home. HFCWO was applied first to the other group and then these patients were hospitalized for CPR. The primary outcome measure of the study was pulmonary function test (PFT). The secondary outcomes were pulse arterial oxygen saturation (SpO(2)) and the perceived efficiency and comfort level. ResultsPFT values of patients increased significantly after both PR methods (before/after): CPR: FVC: 77.014.1/81.8 +/- 13.0 (P=0.002); FEV1: 72.9 +/- 14.8/78.7 +/- 13.5 (P=0.001); PEF: 73.8 +/- 14.5/82.5 +/- 14.5 (P=0.001); FEF25-75: 68.6 +/- 27.6/74.9 +/- 29.3 (P=0.007). HFCWO: FVC: 75.1 +/- 15.3/80.3 +/- 13.9 (P=0.002); FEV1: 71.4 +/- 16/77.4 +/- 14.6 (P=0.001); PEF: 70.9 +/- 18.0/78.3 +/- 17.7 (P=0.002); FEF25-75: 70.5 +/- 23.4/76.4 +/- 25.6 (P=0.006). There were no significant differences in % predicted FVC, FEV1, PEF, and FEF25-75 increased values with CPR and HFCWO. HFCWO was found more comfortable (P=0.04). Two PR methods were found efficient and no desaturation occurred during PR. ConclusionsPFTs were significantly increased after both PR methods. There were no differences in PFTs and SpO(2) between the CPR and HFCWO groups. Both PR methods were found efficient. HFCWO was found more comfortable. HFCWO may be an option in patients with chronic pulmonary disease and low adherence to PR. Pediatr Pulmonol. 2014; 49:611-616. (c) 2013 Wiley Periodicals, Inc.
dc.identifier.doi10.1002/ppul.22861
dc.identifier.eissn1099-0496
dc.identifier.issn8755-6863
dc.identifier.pubmed24039238
dc.identifier.urihttps://hdl.handle.net/11424/237690
dc.identifier.wosWOS:000335392800016
dc.language.isoeng
dc.publisherWILEY-BLACKWELL
dc.relation.ispartofPEDIATRIC PULMONOLOGY
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectairway cleaning techniques
dc.subjectnoncystic fibrosis bronchiectasis
dc.subjectchildren
dc.subjectPOSITIVE EXPIRATORY PRESSURE
dc.subjectCYSTIC-FIBROSIS
dc.subjectCLEARANCE TECHNIQUES
dc.subjectPOSTURAL DRAINAGE
dc.subjectAIRWAY CLEARANCE
dc.subjectCHILDREN
dc.subjectPHYSIOTHERAPY
dc.subjectMANAGEMENT
dc.subjectCOMPRESSION
dc.subjectDIAGNOSIS
dc.titleComparison of Conventional Pulmonary Rehabilitation and High-Frequency Chest Wall Oscillation In Primary Ciliary Dyskinesia
dc.typearticle
dspace.entity.typePublication
local.avesis.id42dbe1f1-f637-45bf-b369-f30b1b407eb8
local.import.packageSS17
local.indexed.atWOS
local.indexed.atSCOPUS
local.indexed.atPUBMED
local.journal.numberofpages6
oaire.citation.endPage616
oaire.citation.issue6
oaire.citation.startPage611
oaire.citation.titlePEDIATRIC PULMONOLOGY
oaire.citation.volume49
relation.isAuthorOfPublication218b489d-97ab-49dd-9db6-0c2a732f1999
relation.isAuthorOfPublication.latestForDiscovery218b489d-97ab-49dd-9db6-0c2a732f1999

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