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The effects of daily alendronate, daily calcitonin and alendronate every other day on bone mineral density in osteoporotic men

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dc.contributor.authorAKYÜZ, GÜLSEREN DERYA
dc.contributor.authorsGuven, Zeynep; Karadag-Saygi, Evrim; Unlu-Ozkan, Feyza; Akyuz, Gulseren
dc.date.accessioned2022-03-12T17:32:10Z
dc.date.available2022-03-12T17:32:10Z
dc.date.issued2007
dc.description.abstractObjectives. Biphosphonates have been widely used in the treatment of osteoporosis, but there is not enough data on their use in men. The aim of this study is to investigate the effects of twelve months' treatment with daily 10 mg alendronate, every other day 10 mg alendronate and daily 200 IU calcitonin on bone mineral density (BMD) in men with osteoporosis. Materials and methods. 46 men with osteoporosis were randomly allocated to three groups: 15 patients in the first group received daily 10 mg alendronate and calcium (1000 mg/day), 14 patients in the second group used every other day 10 mg alendronate and calcium and 17 patients in the third group were given intranasal salmon calcitonin and calcium. At the baseline, sixth and twelfth months, BMD was measured at lumbar spine (L2-4), femoral neck and Ward's triangle zone by means of dual energy X-ray absorptiometry (LUNAR). Results. In daily and every other day alendronate and calcitonin groups there was a significant increase in BMD at lumbar spine (p = 0.004, p = 0.001, p = 0.04), but no difference at the femoral neck (p > 0.05) at the end of twelve months. When the groups were compared with each other, no significant differences in BMD levels at lumbar spine, femoral neck and Ward's triangle were found (p > 0.05).
dc.identifier.doi10.1080/13685530701661051
dc.identifier.issn1368-5538
dc.identifier.pubmed18033629
dc.identifier.urihttps://hdl.handle.net/11424/228484
dc.identifier.wosWOS:000252568000004
dc.language.isoeng
dc.publisherINFORMA HEALTHCARE
dc.relation.ispartofAGING MALE
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectmale osteoporosis
dc.subjectalendronate
dc.subjectcalcitonin
dc.subjectbone mineral density
dc.subjectSPRAY SALMON-CALCITONIN
dc.subjectIDIOPATHIC OSTEOPOROSIS
dc.subjectRANDOMIZED-TRIAL
dc.subjectWOMEN
dc.subjectFRACTURES
dc.titleThe effects of daily alendronate, daily calcitonin and alendronate every other day on bone mineral density in osteoporotic men
dc.typearticle
dspace.entity.typePublication
local.avesis.id6ec3a7eb-8970-4734-91c6-c74af8e96bcb
local.import.packageSS17
local.indexed.atWOS
local.indexed.atSCOPUS
local.indexed.atPUBMED
local.journal.numberofpages5
oaire.citation.endPage201
oaire.citation.issue4
oaire.citation.startPage197
oaire.citation.titleAGING MALE
oaire.citation.volume10
relation.isAuthorOfPublicationa0d3ad8e-a3dd-44d0-98b7-d3eb31f6a0c9
relation.isAuthorOfPublication.latestForDiscoverya0d3ad8e-a3dd-44d0-98b7-d3eb31f6a0c9

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