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The efficacy of Tc99m dimercaptosuccinic acid (Tc-DMSA) scintigraphy and ultrasonography in detecting renal scars in children with primary vesicoureteral reflux (VUR)

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dc.contributor.authorALPAY, HARİKA
dc.contributor.authorsTemiz, Y.; Tarcan, T.; Onol, F. F.; Alpay, H.; Simsek, F.
dc.date.accessioned2022-03-12T17:19:32Z
dc.date.available2022-03-12T17:19:32Z
dc.date.issued2006
dc.description.abstractIntroduction: Pyelonephritis-induced renal scarring in children is a major predisposing factor for proteinuria, hypertension, and ultimate renal failure. The aim of this study was to investigate and compare the efficacy of Tc99m dimercaptosuccinic acid (Tc-DMSA) renal scintigraphy and renal ultrasonography (USG) in detecting renal scars in children with primary vesicoureteral reflux (VUR). Materials and methods: Tc-DMSA scan and USG studies were done in 62 children who were admitted to our clinic between 1997 and 2003 because of documented urinary tract infection (UTI) and diagnosed with primary VUR. Renal scarring detection rates of Tc-DMSA scan and USG were compared according to reflux grades. Results: In the whole group, renal scars were detected by Tc-DMSA scan and USG in 55% and 38% of refluxing units, respectively. Detection rates of Tc-DMSA and USG according to reflux grades were as follows: 47% and 29% in low-grade VUR (grades 1 and 2), 46% and 25% in mid-grade VUR (grade 3), 76% and 65% in high-grade VUR (grades 4 and 5), respectively. Conclusion: USG was found to be an inappropriate study in the detection of renal parenchymal scars, irrespective of the reflux grade. In this study, Tc-DMSA scan detected scars in 35% of kidneys reported to be normal on USG.
dc.identifier.doi10.1007/s11255-005-3829-6
dc.identifier.eissn1573-2584
dc.identifier.issn0301-1623
dc.identifier.pubmed16502071
dc.identifier.urihttps://hdl.handle.net/11424/228121
dc.identifier.wosWOS:000239603900028
dc.language.isoeng
dc.publisherSPRINGER
dc.relation.ispartofINTERNATIONAL UROLOGY AND NEPHROLOGY
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectDMSA scan
dc.subjectrenal scar
dc.subjectultrasonography
dc.subjectvesicoureteral reflux
dc.subjectURINARY-TRACT-INFECTIONS
dc.subjectPOWER DOPPLER SONOGRAPHY
dc.subjectCORTICAL SCINTIGRAPHY
dc.subjectACUTE PYELONEPHRITIS
dc.titleThe efficacy of Tc99m dimercaptosuccinic acid (Tc-DMSA) scintigraphy and ultrasonography in detecting renal scars in children with primary vesicoureteral reflux (VUR)
dc.typearticle
dspace.entity.typePublication
local.avesis.idbb5919b7-383d-4b7b-ae9a-fca3c5e9a622
local.import.packageSS17
local.indexed.atWOS
local.indexed.atSCOPUS
local.indexed.atPUBMED
local.journal.numberofpages4
oaire.citation.endPage152
oaire.citation.issue1
oaire.citation.startPage149
oaire.citation.titleINTERNATIONAL UROLOGY AND NEPHROLOGY
oaire.citation.volume38
relation.isAuthorOfPublication102b331c-4c62-4795-880d-234f6b72fa6a
relation.isAuthorOfPublication.latestForDiscovery102b331c-4c62-4795-880d-234f6b72fa6a

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