Publication:
Multicenter case series of standalone XEN implant vs. combination with phacoemulsification in Turkish patients

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dc.contributor.authorERASLAN, MUHSİN
dc.contributor.authorsEraslan, Muhsin; Ozcan, Altan Atakan; Dericioglu, Volkan; Ciloglu, Emine
dc.date.accessioned2022-03-12T22:57:07Z
dc.date.available2022-03-12T22:57:07Z
dc.date.issued2021
dc.description.abstractPurpose To evaluate and compare the efficacy, safety and needling timing and rates of standalone XEN implant vs. combination with phacoemulsification in Turkish patients. Methods Retrospective, multicenter study which included the data of patients, who had open angle glaucoma including primary open angle glaucoma and pseudoexfoliation glaucoma, underwent standalone XEN implantation (XEN alone) and combined surgery with phacoemulsification (XEN + Phaco) between 2016 and 2018. Results The study included 26 eyes of 24 patients in XEN alone group and 32 eyes of 30 patients in XEN + Phaco group. The mean intraocular pressure (IOP) was 23.3 +/- 6.0 mmHg and 24.4 +/- 7.4 mmHg at baseline (p = 0.838), and it reduced to 16.3 +/- 3.0 mmHg and 16.4 +/- 2.3 mmHg at 12-month follow-up (p = 0.436) in XEN alone and XEN + Phaco groups, respectively (reduction: %30 and %33, P = 0.642). The mean number of medications reduced from 2.9 + 0.7 before surgery to 0.9 + 0.9 on month 12. In XEN alone and XEN + Phaco groups, the needling rates were 42.3% and 31.2% (p = 0.491), and the mean time to needling was 3.7 +/- 3.2 months and 4.9 +/- 8.0 months (p = 0.696), respectively. Hypotonia (17.2%) and hyphema (10.3%) were the most frequent complications, respectively. In XEN alone and XEN + Phaco groups, partial success was achieved in 73.1% and 71.9% of eyes when defined as IOP < 18 mmHg with any medication, respectively (p = 0.920). Conclusion The XEN implant provides significant reduction in IOP and number of medications, either standalone or combination with phacoemulsification. Both procedures need intensive postoperative care, requiring needling in approximately one-third of patients.
dc.identifier.doi10.1007/s10792-021-01899-7
dc.identifier.eissn1573-2630
dc.identifier.issn0165-5701
dc.identifier.pubmed34050406
dc.identifier.urihttps://hdl.handle.net/11424/236998
dc.identifier.wosWOS:000655881400002
dc.language.isoeng
dc.publisherSPRINGER
dc.relation.ispartofINTERNATIONAL OPHTHALMOLOGY
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectXEN implant
dc.subjectMinimally invasive glaucoma surgery
dc.subjectPrimary open angle glaucoma
dc.subjectGlaucoma surgery
dc.subjectPhacoemulsification
dc.subjectINTRAOCULAR-PRESSURE
dc.subjectCATARACT
dc.subjectEFFICACY
dc.subjectGLAUCOMA
dc.subjectSAFETY
dc.subjectREDUCTION
dc.subjectSURGERY
dc.titleMulticenter case series of standalone XEN implant vs. combination with phacoemulsification in Turkish patients
dc.typearticle
dspace.entity.typePublication
local.avesis.id58abc117-d3f1-4e3b-9a12-47ea701d3728
local.import.packageSS17
local.indexed.atWOS
local.indexed.atSCOPUS
local.indexed.atPUBMED
local.journal.numberofpages9
oaire.citation.endPage3379
oaire.citation.issue10
oaire.citation.startPage3371
oaire.citation.titleINTERNATIONAL OPHTHALMOLOGY
oaire.citation.volume41
relation.isAuthorOfPublication22668ace-5f6d-45b8-ab01-b2839b2a5566
relation.isAuthorOfPublication.latestForDiscovery22668ace-5f6d-45b8-ab01-b2839b2a5566

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