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The impact of nail psoriasis on disease activity, quality of life, and clinical variables in patients with psoriatic arthritis: A cross-sectional multicenter study

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dc.contributor.authorACER KASMAN, SEVTAP
dc.contributor.authorDURUÖZ, MEHMET TUNCAY
dc.contributor.authorsCENGİZ G., Nas K., KESKİN Y., Kilic E., Sargin B., ACER KASMAN S., ALKAN H., ŞAHİN N., Balta N. C. , Gezer I. A. , et al.
dc.date.accessioned2022-10-31T17:43:24Z
dc.date.available2022-10-31T17:43:24Z
dc.date.issued2022-09-01
dc.description.abstractAim Nail involvement is common in psoriatic arthritis. This study assesses clinical characteristics, nail psoriasis prevalence, and impact of nail psoriasis on disease activity in patients with psoriatic arthritis (PsA). Method This cross-sectional multicenter study was conducted by the Turkish League Against Rheumatism using PsA patients recruited from 25 centers. Demographic and clinical characteristics of PsA patients, such as disease activity measures, quality of life, and nail involvement findings were assessed during routine follow-up examinations. Patients were divided into two groups according to the presence or absence of nail psoriasis and compared using the chi(2) test or Fisher exact test for categorical variables and the t-test or Mann-Whitney U test for continuous variables. Results In 1122 individuals with PsA, 645 (57.5%) displayed nail psoriasis. The most frequent features of fingernails were ridges (38%), followed by pitting (21%) and onycholysis (19%). More females were present in both groups (with and without nail psoriasis; 64% vs 67%, P < 0.282). Patients with nail psoriasis were older, indicated more pain and fatigue, experienced greater swelling, tender joint counts, and skin disease severity, and had a higher disease activity score compared with those without nail psoriasis (all P < 0.05). Conclusion We demonstrate an increased prevalence of nail psoriasis observed in patients with psoriatic arthritis. Patients with nail involvement experience increased disease activity, lower quality of life, and diminished mental and physical status compared with those without nail involvement.
dc.identifier.citationCENGİZ G., Nas K., KESKİN Y., Kilic E., Sargin B., ACER KASMAN S., ALKAN H., ŞAHİN N., Balta N. C. , Gezer I. A. , et al., "The impact of nail psoriasis on disease activity, quality of life, and clinical variables in patients with psoriatic arthritis: A cross-sectional multicenter study", INTERNATIONAL JOURNAL OF RHEUMATIC DISEASES, 2022
dc.identifier.doi10.1111/1756-185x.14442
dc.identifier.issn1756-1841
dc.identifier.urihttps://hdl.handle.net/11424/282722
dc.language.isoeng
dc.relation.ispartofINTERNATIONAL JOURNAL OF RHEUMATIC DISEASES
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectTıp
dc.subjectDahili Tıp Bilimleri
dc.subjectİç Hastalıkları
dc.subjectİmmünoloji ve Romatoloji
dc.subjectSağlık Bilimleri
dc.subjectMedicine
dc.subjectInternal Medicine Sciences
dc.subjectInternal Diseases
dc.subjectImmunology and Rheumatology
dc.subjectHealth Sciences
dc.subjectROMATOLOJİ
dc.subjectKlinik Tıp
dc.subjectKlinik Tıp (MED)
dc.subjectRHEUMATOLOGY
dc.subjectCLINICAL MEDICINE
dc.subjectClinical Medicine (MED)
dc.subjectRomatoloji
dc.subjectRheumatology
dc.subjectclinical characteristics
dc.subjectdisease activity
dc.subjectnail involvement
dc.subjectnail psoriasis
dc.subjectpsoriatic arthritis
dc.subjectquality of life
dc.subjectDISTAL INTERPHALANGEAL JOINT
dc.subjectANKYLOSING-SPONDYLITIS
dc.subjectSEVERITY INDEX
dc.subjectINVOLVEMENT
dc.subjectEPIDEMIOLOGY
dc.subjectPATHOGENESIS
dc.subjectPREVALENCE
dc.subjectFEATURES
dc.subjectRECOMMENDATIONS
dc.subjectONYCHOLYSIS
dc.subjectclinical characteristics
dc.subjectdisease activity
dc.subjectnail involvement
dc.subjectnail psoriasis
dc.subjectpsoriatic arthritis
dc.subjectquality of life
dc.titleThe impact of nail psoriasis on disease activity, quality of life, and clinical variables in patients with psoriatic arthritis: A cross-sectional multicenter study
dc.typearticle
dspace.entity.typePublication
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