Publication: Oral bisphosphonate therapy for vitamin D intoxication of the infant
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Date
2003
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Publisher
AMER ACAD PEDIATRICS
Abstract
Vitamin D intoxication in infancy has serious consequences attributable to acute hypercalcemia and subsequent hypercalcuria/nephrocalcinosis. Current treatments of patients with vitamin D intoxication are unsatisfactory and associated with prolonged hypercalcemia. We now report the use of oral alendronate sodium in a 3-month-old infant with vitamin D intoxication. Short-term oral alendronate sodium treatment effectively corrected hypercalcemia/hypercalciuria, decreased the duration of hospitalization, and appears safe in 15 months of observation.
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Keywords
bisphosphonates, hypercalcemia, hypervitaminosis D, HYPERCALCEMIA, PAMIDRONATE, CHILDREN