Publication:
The relationships of motor-evoked potentials to hand dexterity, motor function, and spasticity in chronic stroke patients: a transcranial magnetic stimulation study

dc.contributor.authorAKYÜZ, GÜLSEREN DERYA
dc.contributor.authorsCakar, Engin; Akyuz, Gulseren; Durmus, Oguz; Bayman, Levent; Yagci, Ilker; Karadag-Saygi, Evrim; Gunduz, Osman Hakan
dc.date.accessioned2022-03-12T20:29:53Z
dc.date.available2022-03-12T20:29:53Z
dc.date.issued2016
dc.description.abstractThe standardization of patient evaluation and monitoring methods has a special importance in evaluating the effectiveness of therapeutic methods using drugs or rehabilitative techniques in stroke rehabilitation. The aim of this study was to investigate the relationships between clinical instruments and transcranial magnetic stimulation (TMS)-evoked neurophysiological parameters in stroke patients. This study included 22 chronic post-stroke patients who were clinically assessed using the Motricity Index (MI), finger-tapping test (FTT), Motor Activity Log (MAL) 28, Brunnstrom motor staging and Ashworth Scale (ASH). Motor-evoked potential (MEP) latency and amplitude, resting motor threshold (rMT) and central motor conduction time (CMCT) were measured with TMS. Shorter MEP-latency, shorter CMCT, higher motor-evoked potential amplitude, and diminished rMT exhibited significant correlations with clinical measures evaluating motor stage, dexterity, and daily life functionality. rMT exhibited a negative correlation with hand and lower extremity Brunnstrom stages (r = -0.64, r = -0.51, respectively), MI score (r = -0.48), FTT score (r = -0.69), and also with amount of use scale and quality of movement scale of MAL 28 scores (r = -0.61, r = -0.62, respectively). Higher MEP amplitude and diminished rMT showed positive correlations with reduced ASH score (r = -0.65, r = 0.44, respectively). The TMS-evoked neurophysiologic parameters including MEP latency, amplitude, rMT and CMCT generally have positive correlation with clinical measures which evaluate motor stage, dexterity and daily life functionality. Additionally, spasticity has also remarkable relationships with MEP amplitude and rMT. These results suggest that TMS-evoked neurophysiological parameters were useful measures for monitoring post-stroke patients.
dc.identifier.doi10.1007/s13760-016-0633-2
dc.identifier.eissn2240-2993
dc.identifier.issn0300-9009
dc.identifier.pubmed27037821
dc.identifier.urihttps://hdl.handle.net/11424/234130
dc.identifier.wosWOS:000387681300008
dc.language.isoeng
dc.publisherSPRINGER HEIDELBERG
dc.relation.ispartofACTA NEUROLOGICA BELGICA
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectDexterity
dc.subjectMotor-evoked potential
dc.subjectNeurorehabilitation
dc.subjectSpasticity
dc.subjectTranscranial magnetic stimulation
dc.subjectPROGNOSTIC VALUE
dc.subjectSUBCORTICAL STROKE
dc.subjectUPPER EXTREMITY
dc.subjectRECOVERY
dc.subjectPOSTSTROKE
dc.subjectREHABILITATION
dc.subjectTRIALS
dc.subjectSCALES
dc.subjectOUTPUT
dc.subjectINDEX
dc.titleThe relationships of motor-evoked potentials to hand dexterity, motor function, and spasticity in chronic stroke patients: a transcranial magnetic stimulation study
dc.typearticle
dspace.entity.typePublication
local.avesis.id8b69a6a6-b48b-4578-8b74-82d7bfbaaeb6
local.import.packageSS17
local.indexed.atWOS
local.indexed.atSCOPUS
local.indexed.atPUBMED
local.journal.numberofpages7
local.journal.quartileQ3
oaire.citation.endPage487
oaire.citation.issue4
oaire.citation.startPage481
oaire.citation.titleACTA NEUROLOGICA BELGICA
oaire.citation.volume116
relation.isAuthorOfPublicationa0d3ad8e-a3dd-44d0-98b7-d3eb31f6a0c9
relation.isAuthorOfPublication.latestForDiscoverya0d3ad8e-a3dd-44d0-98b7-d3eb31f6a0c9

Files

Collections