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First clinical multicenter experience with the new Pipeline Vantage flow diverter

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dc.contributor.authorBALTACIOĞLU, FEYYAZ
dc.contributor.authorsVollherbst D. F., Cekirge H. S., Saatci I., BALTACIOĞLU F., Onal B., KOÇ O., Rautio R., Sinisalo M., Tomasello A., Vega P., et al.
dc.date.accessioned2023-03-06T10:58:35Z
dc.date.available2023-03-06T10:58:35Z
dc.date.issued2023-01-01
dc.description.abstractBackground Flow diversion is an innovative and increasingly used technique for the treatment of intracranial aneurysms. New flow diverters (FDs) are being introduced to improve the safety and efficacy of this treatment. The aim of this study was to assess the safety, feasibility, and efficacy of the new Pipeline Vantage (PV) FD. Methods Patients with intracranial aneurysms treated with the PV at 10 international neurovascular centers were retrospectively analyzed. Patient and aneurysm characteristics, procedural parameters, complications, and the grade of occlusion were assessed. Results 60 patients with 70 aneurysms (5.0% with acute hemorrhage, 90.0% located in the anterior circulation) were included. 82 PVs were implanted in 61 treatment sessions. The PV could be successfully implanted in all treatments. Additional coiling was performed in 18.6%, and in-stent balloon angioplasty (to enhance the vessel wall apposition) in 24.6%. Periprocedural technical complications occurred in 24.6% of the treatments, were predominantly FD deployment problems, and were all asymptomatic. The overall symptomatic complication rate was 8.2% and the neurological symptomatic complication rate was 3.3%. Only one symptomatic complication was device-related (perforator artery infarctions leading to stroke). After a mean follow-up of 7.1 months, the rate of complete aneurysm occlusion was 77.9%. One patient (1.7%) died due to aneurysmal subarachnoid hemorrhage which occurred before treatment, unrelated to the procedure. Conclusions The new PV FD is safe and feasible for the treatment of intracranial aneurysms. The short-term occlusion rates are promising but need further assessment in prospective long-term follow-up studies.
dc.identifier.citationVollherbst D. F., Cekirge H. S., Saatci I., BALTACIOĞLU F., Onal B., KOÇ O., Rautio R., Sinisalo M., Tomasello A., Vega P., et al., "First clinical multicenter experience with the new Pipeline Vantage flow diverter", JOURNAL OF NEUROINTERVENTIONAL SURGERY, cilt.15, sa.1, ss.63-69, 2023
dc.identifier.doi10.1136/neurintsurg-2021-018480
dc.identifier.endpage69
dc.identifier.issn1759-8478
dc.identifier.issue1
dc.identifier.startpage63
dc.identifier.urihttps://pubmed.ncbi.nlm.nih.gov/35172983/
dc.identifier.urihttps://hdl.handle.net/11424/287171
dc.identifier.volume15
dc.language.isoeng
dc.relation.ispartofJOURNAL OF NEUROINTERVENTIONAL SURGERY
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectTıp
dc.subjectSağlık Bilimleri
dc.subjectCerrahi Tıp Bilimleri
dc.subjectYaşam Bilimleri
dc.subjectTemel Bilimler
dc.subjectMedicine
dc.subjectHealth Sciences
dc.subjectSurgery Medicine Sciences
dc.subjectLife Sciences
dc.subjectNatural Sciences
dc.subjectNÖRO-GÖRÜNTÜLEME
dc.subjectSinirbilim ve Davranış
dc.subjectYaşam Bilimleri (LIFE)
dc.subjectCERRAHİ
dc.subjectKlinik Tıp
dc.subjectKlinik Tıp (MED)
dc.subjectNEUROIMAGING
dc.subjectNEUROSCIENCE & BEHAVIOR
dc.subjectLife Sciences (LIFE)
dc.subjectSURGERY
dc.subjectCLINICAL MEDICINE
dc.subjectClinical Medicine (MED)
dc.subjectHuman-Computer Interaction
dc.subjectSurgery
dc.subjectPhysical Sciences
dc.subjectaneurysm
dc.subjectflow diverter
dc.subjectangiography
dc.subjectintervention
dc.subjectINTRACRANIAL ANEURYSMS
dc.subjectEMBOLIZATION DEVICE
dc.titleFirst clinical multicenter experience with the new Pipeline Vantage flow diverter
dc.typearticle
dspace.entity.typePublication
local.avesis.id8000eb48-61f8-4c1f-adc3-05557c188df3
local.indexed.atWOS
local.indexed.atPUBMED
local.indexed.atSCOPUS
relation.isAuthorOfPublication14b6381a-4f6e-4ff9-92f6-842a481bc163
relation.isAuthorOfPublication.latestForDiscovery14b6381a-4f6e-4ff9-92f6-842a481bc163

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