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The effect of a single application of different fluoride varnishes on enamel subsurface lesions in vitro

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dc.contributor.authorŞEN YAVUZ, BETÜL
dc.contributor.authorYILMAZ, MÜESSER AHU
dc.contributor.authorOKTAY, NİHAL ŞEHKAR
dc.contributor.authorKARGÜL, BETÜL
dc.contributor.authorsYildiz P. K., ŞEN YAVUZ B., YILMAZ M. A., OKTAY N. Ş., KARGÜL B.
dc.date.accessioned2022-12-28T08:34:33Z
dc.date.available2022-12-28T08:34:33Z
dc.date.issued2022-04-01
dc.description.abstractThis in vitro study aimed to evaluate the therapeutic effect of different fluoride ion (F) varnish formulations for controlling the carious development of enamel subsurface lesions and the F release into artificial saliva for 2 hr, 24 hr, 48 hr, and 7 days. Artificial enamel carious lesions were created and divided into 6 groups (5 varnish groups and a control group). Varnishes were applied to enamel specimens and then the specimens were incubated in artificial saliva, with the artificial saliva replenished daily. Varnish was removed and lesions were remineralized in artificial saliva for 24 hr. Surface microhardness was measured three times: (i) initially, (ii) after creating the artificial enamel lesions, and (iii) after applying the varnishes. The F release was analyzed after 2 hr, 24 hr, 48 hr, and 7 days of exposure using an ion-selective electrode. Data were analyzed using a One-way Analysis of Variance with the Tukey-Kramer Multiple Comparisons test and the Kruskal-Wallis test with the Dunns Multiple Comparisons test. The highest percentage surface microhardness recovery was found for the treatment with the MI Varnish. According to the percentage surface microhardness recovery results, a statistically significant difference was found between the varnishes and the control group (p < 0.05 and < 0.001). All varnishes released measurable levels of fluoride ions. However, the release of F was the highest in the MI Varnish group (p < 0.01). Duraphat, Enamel Pro Varnish, and MI Varnish released the most F into artificial saliva. Calcium phosphate-based F varnishes improve the capacity of the enamel surface re -hardening. CPP containing F varnish had the highest release of F as compared to the other F releasing varnishes. Further in vivo investigations are also required to prove the clinical applications of the different ingredients containing varnishes.
dc.identifier.citationYildiz P. K., ŞEN YAVUZ B., YILMAZ M. A., OKTAY N. Ş., KARGÜL B., "THE EFFECT OF A SINGLE APPLICATION OF DIFFERENT FLUORIDE VARNISHES ON ENAMEL SUBSURFACE LESIONS IN VITRO", FLUORIDE, cilt.55, sa.2, ss.121-130, 2022
dc.identifier.endpage130
dc.identifier.issn0015-4725
dc.identifier.issue2
dc.identifier.startpage121
dc.identifier.urihttps://www.webofscience.com/wos/woscc/full-record/WOS:000888257000004
dc.identifier.urihttps://hdl.handle.net/11424/284424
dc.identifier.volume55
dc.language.isoeng
dc.relation.ispartofFLUORIDE
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectEczacılık
dc.subjectMeslek Bilimleri
dc.subjectFarmasötik Toksikoloji
dc.subjectSosyal ve Beşeri Bilimler
dc.subjectSosyoloji
dc.subjectYaşam Bilimleri
dc.subjectSağlık Bilimleri
dc.subjectTemel Bilimler
dc.subjectPharmacology and Therapeutics
dc.subjectProfessional Sciences
dc.subjectPharmaceutical Toxicology
dc.subjectSocial Sciences and Humanities
dc.subjectSociology
dc.subjectLife Sciences
dc.subjectHealth Sciences
dc.subjectNatural Sciences
dc.subjectKAMU, ÇEVRE VE İŞ SAĞLIĞI
dc.subjectSosyal Bilimler Genel
dc.subjectSosyal Bilimler (SOC)
dc.subjectTOKSİKOLOJİ
dc.subjectFarmakoloji ve Toksikoloji
dc.subjectYaşam Bilimleri (LIFE)
dc.subjectPUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH
dc.subjectSOCIAL SCIENCES, GENERAL
dc.subjectSocial Sciences (SOC)
dc.subjectTOXICOLOGY
dc.subjectPHARMACOLOGY & TOXICOLOGY
dc.subjectLife Sciences (LIFE)
dc.subjectİş Sağlığı ve Terapisi
dc.subjectGüvenlik Araştırması
dc.subjectSağlık (sosyal bilimler)
dc.subjectGenel Sosyal Bilimler
dc.subjectToksikoloji
dc.subjectFarmakoloji, Toksikoloji ve Eczacılık (çeşitli)
dc.subjectHalk, Çevre ve İş Sağlığı
dc.subjectEpidemiyoloji
dc.subjectSağlık, Toksikoloji ve Mutajenez
dc.subjectFizik Bilimleri
dc.subjectSosyal Bilimler ve Beşeri Bilimler
dc.subjectOccupational Therapy
dc.subjectSafety Research
dc.subjectHealth (social science)
dc.subjectGeneral Social Sciences
dc.subjectToxicology
dc.subjectPharmacology, Toxicology and Pharmaceutics (miscellaneous)
dc.subjectPublic Health, Environmental and Occupational Health
dc.subjectEpidemiology
dc.subjectHealth, Toxicology and Mutagenesis
dc.subjectPhysical Sciences
dc.subjectSocial Sciences & Humanities
dc.subjectCPP-ACP
dc.subjectDemineralization
dc.subjectFluoride release
dc.subjectFluoride varnishes
dc.subjectMicrohardness
dc.subjectRemineralization
dc.subjectTricalcium phosphate
dc.titleThe effect of a single application of different fluoride varnishes on enamel subsurface lesions in vitro
dc.typearticle
dspace.entity.typePublication
local.avesis.id6c4085c5-a32b-4e1a-bc46-e849b2bccd90
local.indexed.atWOS
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