Publication:
Caries Preventive Effects of Theobromine Containing Toothpaste on Early Childhood Caries: Preliminary Results

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dc.contributor.authorKARGÜL, BETÜL
dc.contributor.authorsDurhan, Muesser Ahu; Bisel, Seda Ozsalih; Gokkaya, Berna; Yildiz, Pinar Kulan; Kargul, Betul
dc.date.accessioned2022-03-14T09:55:29Z
dc.date.available2022-03-14T09:55:29Z
dc.date.issued2021-03-15
dc.description.abstractObjective: Enamel remineralizing effects of theobromine have received much attention from the clinicians. The aim of this study was to investigate the caries preventive effect of theobromine containing toothpaste on children with early childhood caries (ECC). Materials & Methods: Salivary pH, buffering capacity and frequency of Streptococcus mutans (SM) levels were measured. Each child was assigned either fluoridated or theobromine containing toothpaste. The changes were analyzed using Laser Fluorescence system. Statistical analyses were performed. Results: We included 13 children (mean age 4.25) with 145 teeth in the fluoridated toothpaste (Colgate Kids toothpaste) group; 13 children (mean age 4.46) with 115 teeth in theobromine containing toothpaste (Theodent (TM) Kids toothpaste) group. Both toothpastes demonstrated enamel remineralization and were effective in increasing the buffering capacity and pH (p < 0.05). A statistically significant decrease in S. mutans levels was found in both toothpaste groups (p<0.05). Conclusion: Both toothpaste group showed a statistically significant amount of enamel remineralization. Since theobromine had the added benefits of increasing the salivary pH and decreasing the S.mutans levels, theobromine containing toothpastes can be considered effective agents in remineralizing white spot lesions and can be used in prevention of early enamel lesions.
dc.identifier.doi10.15644/asc55/1/3
dc.identifier.eissn1846-0410
dc.identifier.issn0001-7019
dc.identifier.pubmed33867534
dc.identifier.urihttps://hdl.handle.net/11424/243669
dc.identifier.wosWOS:000641757000003
dc.language.isoeng
dc.publisherUNIV ZAGREB, SCH DENTAL MEDICINE
dc.relation.ispartofACTA STOMATOLOGICA CROATICA
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectToothpastes
dc.subjectTheobromine
dc.subjectTooth Remineralization
dc.subjectPreventive Dentistry
dc.subjectPreschool Child
dc.subjectHAMSTER CARIES
dc.subjectENAMEL SURFACE
dc.subject1ST MOLARS
dc.subjectREMINERALIZATION
dc.subjectINHIBITION
dc.subjectEXPERIENCE
dc.subjectFLUORIDE
dc.subjectCHILDREN
dc.subjectLESIONS
dc.subjectCOCOA
dc.titleCaries Preventive Effects of Theobromine Containing Toothpaste on Early Childhood Caries: Preliminary Results
dc.typearticle
dspace.entity.typePublication
local.avesis.id11d72f42-5e8b-46cf-9aea-d48ed6dbee94
local.import.packageSS16
local.indexed.atWOS
local.indexed.atSCOPUS
local.indexed.atPUBMED
local.journal.numberofpages10
oaire.citation.endPage27
oaire.citation.issue1
oaire.citation.startPage18
oaire.citation.titleACTA STOMATOLOGICA CROATICA
oaire.citation.volume55
relation.isAuthorOfPublicationa71f3f88-8c68-4f36-a839-8075ced494e8
relation.isAuthorOfPublication.latestForDiscoverya71f3f88-8c68-4f36-a839-8075ced494e8

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