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Effect of Remineralization Agents on Molar-Incisor Hypomineralization-Affected Incisors: A Randomized Controlled Clinical Trial

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dc.contributor.authorKARGÜL, BETÜL
dc.contributor.authorsSEZER B., KARGÜL B.
dc.date.accessioned2023-07-31T09:18:44Z
dc.date.available2023-07-31T09:18:44Z
dc.date.issued2022-01-01
dc.description.abstractObjective: The objective of this study was to evaluate the remineralization effect of two different mineral containing agents on white/creamy and yellow/brown demarcated opacities in incisors in children with molar-incisor hypomineralization (MIH) by using laser fluoresence (LF). Study Design: Fifty-three children (n=401 lesions) with MIH were randomly divided into three groups: (1)calcium glycerophosphate (CaGP), (2)casein phosphopeptide amorphous calcium fluoride phosphate (CPP-ACFP) and, (3)control (1450 ppm fluoride toothpaste). Remineralization was evaluated by means of LF, at baseline, after one and threemonths. Anova Test for Repeated Measurements in intra-group comparisons in evaluating the effectiveness of remineralization agents. One-way Variance Analysis (ANOVA) and Tukey-Kramer Multiple Comparison test were used in the comparisons between groups and, Student Newman Keuls Multpile Comparison Test was used to determine the differences between the measurement averages in case of p<0.05. Results: There was a significant improvement in MIH-lesions over time in all groups (p<0.001), with no differences between groups. The highest percentage of change was observed in CPP-ACFP in lesions LF≤20 scores and the mean percentage of change LF>20 scores, the highest percentage changes in CaGP. There was no significant difference between the groups over the time for all the used outcome measures (p>0.05). Conclusion: The additional use of both mineral containing agents in MIH-affected teeth improved these hypomineralized lesions with mineral deposition. Even if both agents could be used in the hypomineralized teeth with demarcated opacities, future studies are recommended the long-term effect of these mineral containing agents with longer observation and a larger sample size. Keywords: Molar incisor hypomineralization, Calcium glycerophosphate, Casein phosphopeptideamorphous calcium phosphate nanocomplex, Tooth remineralization.
dc.identifier.citationSEZER B., KARGÜL B., "Effect of Remineralization Agents on Molar-Incisor Hypomineralization-Affected Incisors: A Randomized Controlled Clinical Trial", JOURNAL OF CLINICAL PEDIATRIC DENTISTRY, cilt.46, sa.3, ss.192-198, 2022
dc.identifier.doi10.17796/1053-4625-46.3.4
dc.identifier.endpage198
dc.identifier.issn1053-4628
dc.identifier.issue3
dc.identifier.startpage192
dc.identifier.urihttps://meridian.allenpress.com/jcpd/article/46/3/192/483841/Effect-of-Remineralization-Agents-on-Molar-Incisor
dc.identifier.urihttps://hdl.handle.net/11424/291808
dc.identifier.volume46
dc.language.isoeng
dc.relation.ispartofJOURNAL OF CLINICAL PEDIATRIC DENTISTRY
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectTıp
dc.subjectSağlık Bilimleri
dc.subjectDahili Tıp Bilimleri
dc.subjectÇocuk Sağlığı ve Hastalıkları
dc.subjectDiş Hekimliği
dc.subjectMedicine
dc.subjectHealth Sciences
dc.subjectInternal Medicine Sciences
dc.subjectChild Health and Diseases
dc.subjectDentistry
dc.subjectDİŞ HEKİMLİĞİ, ORAL CERRAHİ VE TIP
dc.subjectKlinik Tıp
dc.subjectKlinik Tıp (MED)
dc.subjectPEDİATRİ
dc.subjectDENTISTRY, ORAL SURGERY & MEDICINE
dc.subjectCLINICAL MEDICINE
dc.subjectClinical Medicine (MED)
dc.subjectPEDIATRICS
dc.subjectPeriodontoloji
dc.subjectOrtodonti
dc.subjectAğız Cerrahisi
dc.subjectDiş Hijyeni
dc.subjectDişçilik Hizmetleri
dc.subjectDiş Hekimliği (çeşitli)
dc.subjectPediatri
dc.subjectPediatri, Perinatoloji ve Çocuk Sağlığı
dc.subjectPeriodontics
dc.subjectOrthodontics
dc.subjectOral Surgery
dc.subjectDental Hygiene
dc.subjectDental Assisting
dc.subjectDentistry (miscellaneous)
dc.subjectGeneral Dentistry
dc.subjectPediatrics
dc.subjectPediatrics, Perinatology and Child Health
dc.subjectMolar incisor hypomineralization
dc.subjectCalcium glycerophosphate
dc.subjectCasein phosphopeptide-amorphous calcium phosphate nanocomplex
dc.subjectTooth remineralization
dc.subjectAMORPHOUS CALCIUM-PHOSPHATE
dc.subjectLOW-FLUORIDE DENTIFRICES
dc.subjectCASEIN PHOSPHOPEPTIDE
dc.subjectGLYCEROPHOSPHATE
dc.subjectDEMINERALIZATION
dc.subjectTEETH
dc.subjectDIAGNOSIS
dc.subjectCHILDREN
dc.subjectCARIES
dc.subjectMIH
dc.subjectMolar incisor hypomineralization
dc.subjectCalcium glycerophosphate
dc.subjectTooth remineralization
dc.titleEffect of Remineralization Agents on Molar-Incisor Hypomineralization-Affected Incisors: A Randomized Controlled Clinical Trial
dc.typearticle
dspace.entity.typePublication
local.avesis.id62cd51f0-b2da-4fcb-af7c-87898fd6c8b6
local.indexed.atWOS
local.indexed.atPUBMED
local.indexed.atSCOPUS
relation.isAuthorOfPublicationa71f3f88-8c68-4f36-a839-8075ced494e8
relation.isAuthorOfPublication.latestForDiscoverya71f3f88-8c68-4f36-a839-8075ced494e8

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