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Could Sublingual Immunotherapy Affect Oral Health in Children with Asthma and/or Allergic Rhinitis Sensitized to House Dust Mite?

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dc.contributor.authorÖZEN, AHMET OĞUZHAN
dc.contributor.authorsKiykim, Ayca; Mumcu, Gonca; Ogulur, Ismail; Karakoc-Aydiner, Elif; Direskeneli, Haner; Baris, Safa; Cagan, Hasret; Ozen, Ahmet
dc.date.accessioned2022-03-12T20:31:53Z
dc.date.available2022-03-12T20:31:53Z
dc.date.issued2017
dc.description.abstractBackground: Sublingual immunotherapy (SLIT) has been successfully employed in IgE-mediated respiratory allergies. However, it is not known whether the modulation of immune responses in the sublingual area during SLIT has any deleterious effect on oral health. We sought to determine the oral health prospectively in children receiving SLIT for house dust mite allergy. Material and Methods: Eighteen children with allergic asthma and/or rhinitis and 31 agematched healthy controls (HC) were included in an openlabeled trial. Oral health was evaluated by scoring the decayed, missing, and filled teeth for primary (dmft) and permanent (DMFT) dentition, and the plaque and gingival indices. Moreover, cariogenic food intake and teeth-brushing habits were also noted at baseline and at 19 months. Results: The mean age of the SLIT participants was 9.5 +/- 3.1 years and that of the HC was 9.2 +/- 3.7 years. The mean duration of SLIT was 19.13 +/- 3.81 months. At baseline, the total dmft and DMFT indices were similar in the SLIT and HC groups (p > 0.05), which demonstrated poor hygiene overall. In the within-group comparisons at the examination at 19 months, the SLIT group had a lower number of carious primary teeth and a higher number of filled primary teeth compared to the count at baseline (p = 0.027 and p = 0.058, respectively). Conclusion: Our study showed no detrimental effect of SLIT on oral health during a period of 19 months of follow-up. Parents should be motivated to use dental health services to prevent new caries formation since our cohort had overall poor oral hygiene at the baseline. (C) 2017 S. Karger AG, Basel
dc.identifier.doi10.1159/000480082
dc.identifier.eissn1423-0097
dc.identifier.issn1018-2438
dc.identifier.pubmed28950285
dc.identifier.urihttps://hdl.handle.net/11424/234338
dc.identifier.wosWOS:000413956900007
dc.language.isoeng
dc.publisherKARGER
dc.relation.ispartofINTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectAsthma
dc.subjectRhinitis
dc.subjectAllergy
dc.subjectHouse dust mite
dc.subjectSublingual immunotherapy
dc.subjectCaries
dc.subjectOral health
dc.subjectCARIES
dc.subjectBIOFILMS
dc.subjectPLAQUE
dc.subjectCELLS
dc.titleCould Sublingual Immunotherapy Affect Oral Health in Children with Asthma and/or Allergic Rhinitis Sensitized to House Dust Mite?
dc.typearticle
dspace.entity.typePublication
local.avesis.id9ae30dfa-f664-40fb-818e-2e62a83c22ce
local.import.packageSS17
local.indexed.atWOS
local.indexed.atSCOPUS
local.indexed.atPUBMED
local.journal.numberofpages5
local.journal.quartileQ3
oaire.citation.endPage56
oaire.citation.issue1
oaire.citation.startPage52
oaire.citation.titleINTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY
oaire.citation.volume174
relation.isAuthorOfPublication3e9c297b-e636-4836-8f61-dc9c8b7c29cf
relation.isAuthorOfPublication.latestForDiscovery3e9c297b-e636-4836-8f61-dc9c8b7c29cf

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