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Maternal Thyroid Dysfunction and Neonatal Thyroid Problems

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dc.contributor.authorBEREKET, ABDULLAH
dc.contributor.authorsOzdemir, Hulya; Akman, Ipek; Coskun, Senay; Demirel, Utku; Turan, Serap; Bereket, Abdullah; Bilgen, Hulya; Ozek, Eren
dc.date.accessioned2022-03-14T10:55:42Z
dc.date.available2022-03-14T10:55:42Z
dc.date.issued2013
dc.description.abstractAim. To investigate obstetric features of pregnant women with thyroid disorders and thyroid function tests of their newborn infants. Methods. Women with hypothyroidism and having anti-thyroglobulin (ATG) and anti-thyroid peroxidase (anti-TPO) antibodies were assigned as group I, women with hypothyroidism who did not have autoantibodies were assigned as group II, and women without thyroid problems were assigned as group III. Results. Pregnant women with autoimmune hypothyroidism (group I) had more preterm delivery and their babies needed more frequent neonatal intensive care unit (NICU) admission. In group I, one infant was diagnosed with compensated hypothyroidism and one infant had transient hyperthyrotropinemia. Five infants (23.8%) in group II had thyroid-stimulating hormone (TSH) levels >20 mIU/mL. Only two of them had TSH level >7 mIU/L at the 3rd postnatal week, and all had normal free T4 (FT4). Median maternal TSH level of these five infants with TSH >20 mIU/mL was 6.6 mIU/mL. In group III, six infants (6.5%) had TSH levels above >20 mIU/mL at the 1st postnatal week. Conclusion. Infants of mothers with thyroid problems are more likely to have elevated TSH and higher recall rate on neonatal thyroid screening. Women with thyroid disorders and their newborn infants should be followed closely for both obstetrical problems and for thyroid dysfunction.
dc.identifier.doi10.1155/2013/987843
dc.identifier.eissn1687-8345
dc.identifier.issn1687-8337
dc.identifier.pubmed23737782
dc.identifier.urihttps://hdl.handle.net/11424/245489
dc.identifier.wosWOS:000318931000001
dc.language.isoeng
dc.publisherHINDAWI LTD
dc.relation.ispartofINTERNATIONAL JOURNAL OF ENDOCRINOLOGY
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectTRANSIENT CONGENITAL HYPOTHYROIDISM
dc.subjectEARLY-PREGNANCY
dc.subjectSUBCLINICAL HYPOTHYROIDISM
dc.subjectHORMONE PARAMETERS
dc.subjectCONSEQUENCES
dc.subjectANTIBODIES
dc.subjectMANAGEMENT
dc.subjectGESTATION
dc.subjectINFANT
dc.subjectWOMEN
dc.titleMaternal Thyroid Dysfunction and Neonatal Thyroid Problems
dc.typearticle
dspace.entity.typePublication
local.avesis.id63338821-b917-4c61-a045-a41d1689fde3
local.import.packageSS16
local.indexed.atWOS
local.indexed.atSCOPUS
local.indexed.atPUBMED
local.journal.articlenumber987843
local.journal.numberofpages6
oaire.citation.titleINTERNATIONAL JOURNAL OF ENDOCRINOLOGY
oaire.citation.volume2013
relation.isAuthorOfPublication669e9474-4e39-453f-a4bc-4ede9cb5abac
relation.isAuthorOfPublication.latestForDiscovery669e9474-4e39-453f-a4bc-4ede9cb5abac

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