Publication:
Characteristics and outcomes of carbapenemase harbouring carbapenem-resistant Klebsiella spp. bloodstream infections: a multicentre prospective cohort study in an OXA-48 endemic setting

Simple item page
dc.contributor.authorTİGEN, ELİF
dc.contributor.authorsIsler B., Ozer B., ÇINAR G., ASLAN A. T., Vatansever C., Falconer C., Dolapci I., Simsek F., TÜLEK N., Demirkaya H., et al.
dc.date.accessioned2023-04-03T10:26:42Z
dc.date.accessioned2026-01-11T17:13:27Z
dc.date.available2023-04-03T10:26:42Z
dc.date.issued2022-05-01
dc.description.abstractA prospective, multicentre observational cohort study of carbapenem-resistant Klebsiella spp. (CRK) bloodstream infections was conducted in Turkey from June 2018 to June 2019. One hundred eighty-seven patients were recruited. Single OXA-48-like carbapenemases predominated (75%), followed by OXA-48-like/NDM coproducers (16%). OXA-232 constituted 31% of all OXA-48-like carbapenemases and was mainly carried on ST2096. Thirty-day mortality was 44% overall and 51% for ST2096. In the multivariate cox regression analysis, SOFA score and immunosuppression were significant predictors of 30-day mortality and ST2096 had a non-significant effect. All OXA-48-like producers remained susceptible to ceftazidime-avibactam.
dc.identifier.citationIsler B., Ozer B., ÇINAR G., ASLAN A. T., Vatansever C., Falconer C., Dolapci I., Simsek F., TÜLEK N., Demirkaya H., et al., "Characteristics and outcomes of carbapenemase harbouring carbapenem-resistant Klebsiella spp. bloodstream infections: a multicentre prospective cohort study in an OXA-48 endemic setting", EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES, cilt.41, sa.5, ss.841-847, 2022
dc.identifier.doi10.1007/s10096-022-04425-4
dc.identifier.endpage847
dc.identifier.issn0934-9723
dc.identifier.issue5
dc.identifier.startpage841
dc.identifier.urihttps://pubmed.ncbi.nlm.nih.gov/35301623/
dc.identifier.urihttps://hdl.handle.net/11424/288094
dc.identifier.volume41
dc.language.isoeng
dc.relation.ispartofEUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectYaşam Bilimleri
dc.subjectTemel Bilimler
dc.subjectLife Sciences
dc.subjectNatural Sciences
dc.subjectBULAŞICI HASTALIKLAR
dc.subjectİmmünoloji
dc.subjectYaşam Bilimleri (LIFE)
dc.subjectMikrobiyoloji
dc.subjectINFECTIOUS DISEASES
dc.subjectIMMUNOLOGY
dc.subjectLife Sciences (LIFE)
dc.subjectMICROBIOLOGY
dc.subjectGeneral Immunology and Microbiology
dc.subjectImmunology
dc.subjectInfectious Diseases
dc.subjectHealth Sciences
dc.subjectOXA-48
dc.subjectOXA-232
dc.subjectST2096
dc.subjectKlebsiella pneumoniae
dc.subjectCeftazidime-avibactam
dc.subjectPNEUMONIAE
dc.subjectENTEROBACTERALES
dc.subjectCOPRODUCTION
dc.subjectSPREAD
dc.subjectNDM-1
dc.subjectOXA-48
dc.subjectOXA-232
dc.subjectST2096
dc.subjectKlebsiella pneumoniae
dc.subjectCeftazidime-avibactam
dc.titleCharacteristics and outcomes of carbapenemase harbouring carbapenem-resistant Klebsiella spp. bloodstream infections: a multicentre prospective cohort study in an OXA-48 endemic setting
dc.typearticle
dspace.entity.typePublication

Files

Original bundle

Now showing 1 - 1 of 1
Thumbnail Image
Name:
file.pdf
Size:
948.11 KB
Format:
Adobe Portable Document Format
Download

Collections

Araştırma Çıktıları