Publication:
Association Between Severe Vitamin D Deficiency, Lung Function and Asthma Control

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dc.contributor.authorCEYHAN, BERRİN
dc.contributor.authorsBeyhan-Sagmen, Seda; Baykan, Ozgur; Balcan, Baran; Ceyhan, Berrin
dc.date.accessioned2022-03-12T20:31:19Z
dc.date.available2022-03-12T20:31:19Z
dc.date.issued2017
dc.description.abstractIntroduction: To examine the relationship between severe vitamin D deficiency, asthma control, and pulmonary function in Turkish adults with asthma. Methods: One hundred six asthmatic patients underwent pulmonary function tests skin prick test, peripheral blood eosinophil counts, IgE, body mass index and vitamin D levels were determined. Patients were divided into 2 subgroups according to vitamin D levels (vitamin D level < 10 ng/ml and vitamin D level >= 10 ng/ml). Asthma control tests were performed. Results: The mean age of subgroup I (vitamin D level < 10) was 37 +/- 10 and the mean age of subgroup II (vitamin D level >= 10 ng/ml) was 34 +/- 8. Sixty-six percent of patients had severe vitamin D deficiency (vitamin D level < 10 ng/m1). There was a significant trend towards lower absolute FEV1 (L) values in patients with lower vitamin D levels (P=.001). Asthma control test scores were significantly low in the severe deficiency group than the other group (P=.02). There were a greater number of patients with uncontrolled asthma (asthma control test scores < 20) in the severe vitamin D deficiency group (P=.040). Patients with severe vitamin D deficiency had a higher usage of inhaled corticosteroids than the group without severe vitamin D deficiency (P=.015). There was a significant trend towards lower absolute FEV1 (L) (P=.005, r =.272) values in patients with lower vitamin D levels. Vitamin D levels were inversely related with body mass index (P=.046). Conclusion: The incidence of severe vitamin D deficiency was high in adult Turkish asthmatics. In addition,lower vitamin D levels were associated with poor asthma control and decreased pulmonary function.(C) 2016 SEPAR. Published by Elsevier Espana, S.L.U. All rights reserved.
dc.identifier.doi10.1016/j.arbres.2016.09.010
dc.identifier.eissn1579-2129
dc.identifier.issn0300-2896
dc.identifier.pubmed28320552
dc.identifier.urihttps://hdl.handle.net/11424/234275
dc.identifier.wosWOS:000399967200006
dc.language.isospa
dc.publisherELSEVIER ESPANA SLU
dc.relation.ispartofARCHIVOS DE BRONCONEUMOLOGIA
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectAsthma control
dc.subjectFEV1
dc.subjectPulmonary function
dc.subjectSevere vitamin D deficiency
dc.subjectSERUM 25-HYDROXYVITAMIN D
dc.subjectSMOOTH-MUSCLE-CELLS
dc.subject3RD NATIONAL-HEALTH
dc.subjectCHILDHOOD ASTHMA
dc.subjectD INSUFFICIENCY
dc.subjectADULTS
dc.subjectDISEASE
dc.titleAssociation Between Severe Vitamin D Deficiency, Lung Function and Asthma Control
dc.typearticle
dspace.entity.typePublication
local.avesis.id3de17218-e096-40ba-b9e2-45e4ed2d0207
local.import.packageSS17
local.indexed.atWOS
local.indexed.atPUBMED
local.journal.numberofpages6
local.journal.quartileQ2
oaire.citation.endPage191
oaire.citation.issue4
oaire.citation.startPage186
oaire.citation.titleARCHIVOS DE BRONCONEUMOLOGIA
oaire.citation.volume53
relation.isAuthorOfPublication14f2d015-b03a-45e7-bb38-e82572308bca
relation.isAuthorOfPublication.latestForDiscovery14f2d015-b03a-45e7-bb38-e82572308bca

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