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Characteristics, management, and outcomes of patients with left-sided infective endocarditis complicated by heart failure: a substudy of the ESC-EORP EURO-ENDO (European infective endocarditis) registry

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dc.contributor.authorMUTLU, BÜLENT
dc.contributor.authorsBohbot Y., Habib G., Laroche C., Stohr E., Chirouze C., Hernandez-Meneses M., Melissopoulou M., Mutlu B., Scheggi V., Branco L., et al.
dc.date.accessioned2023-05-29T07:42:07Z
dc.date.available2023-05-29T07:42:07Z
dc.date.issued2022-07-01
dc.description.abstractAims To evaluate the current management and survival of patients with left-sided infective endocarditis (IE) complicated by congestive heart failure (CHF) in the ESC-EORP European Endocarditis (EURO-ENDO) registry. Methods and results Among the 3116 patients enrolled in this prospective registry, 2449 (mean age: 60years, 69% male) with left-sided (native or prosthetic) IE were included in this study. Patients with CHF (n = 698, 28.5%) were older, with more comorbidity and more severe valvular damage (mitro-aortic involvement, vegetations >10 mm and severe regurgitation/new prosthesis dehiscence) than those without CHF (all p 10 mm, severe valvular regurgitation and/or new prosthetic dehiscence, perivalvular complication, and prosthetic IE (OR 0.22, 95% CI 0.12-0.38; p < 0.001) and in 1-year mortality (HR 0.29, 95% CI 0.20-0.41; p < 0.001). Conclusion Congestive heart failure is common in left-sided IE and is associated with older age, greater comorbidity, more advanced lesions, and markedly higher 30-day and 1-year mortality. Early surgery is strongly associated with lower mortality but is performed on only approximately half of patients with CHF, mainly because of a surgical risk considered prohibitive.
dc.identifier.citationBohbot Y., Habib G., Laroche C., Stohr E., Chirouze C., Hernandez-Meneses M., Melissopoulou M., Mutlu B., Scheggi V., Branco L., et al., "Characteristics, management, and outcomes of patients with left-sided infective endocarditis complicated by heart failure: a substudy of the ESC-EORP EURO-ENDO (European infective endocarditis) registry", EUROPEAN JOURNAL OF HEART FAILURE, cilt.24, ss.1253-1265, 2022
dc.identifier.doi10.1002/ejhf.2525
dc.identifier.endpage1265
dc.identifier.issn1388-9842
dc.identifier.startpage1253
dc.identifier.urihttps://pubmed.ncbi.nlm.nih.gov/35508915/
dc.identifier.urihttps://hdl.handle.net/11424/289694
dc.identifier.volume24
dc.language.isoeng
dc.relation.ispartofEUROPEAN JOURNAL OF HEART FAILURE
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectTıp
dc.subjectSağlık Bilimleri
dc.subjectDahili Tıp Bilimleri
dc.subjectKardiyoloji
dc.subjectMedicine
dc.subjectHealth Sciences
dc.subjectInternal Medicine Sciences
dc.subjectCardiovascular
dc.subjectKALP VE KALP DAMAR SİSTEMLERİ
dc.subjectKlinik Tıp
dc.subjectKlinik Tıp (MED)
dc.subjectCARDIAC & CARDIOVASCULAR SYSTEMS
dc.subjectCLINICAL MEDICINE
dc.subjectClinical Medicine (MED)
dc.subjectKardiyoloji ve Kardiyovasküler Tıp
dc.subjectCardiology and Cardiovascular Medicine
dc.subjectInfective endocarditis
dc.subjectCongestive heart failure
dc.subjectSurvival
dc.subjectOutcome
dc.subjectEarly surgery
dc.subjectEURO-ENDO
dc.subjectNATIVE VALVE ENDOCARDITIS
dc.subjectPROGNOSTIC-FACTORS
dc.subjectMORTALITY
dc.subjectSURGERY
dc.subjectRISK
dc.subjectPREDICTORS
dc.subjectADULTS
dc.subjectIMPACT
dc.subjectDEATH
dc.subjectInfective endocarditis
dc.subjectCongestive heart failure
dc.subjectSurvival
dc.subjectOutcome
dc.subjectEarly surgery
dc.subjectEURO-ENDO
dc.titleCharacteristics, management, and outcomes of patients with left-sided infective endocarditis complicated by heart failure: a substudy of the ESC-EORP EURO-ENDO (European infective endocarditis) registry
dc.typearticle
dspace.entity.typePublication
local.avesis.id997d4d1a-a70b-4f43-8593-42ca61a9b15a
local.indexed.atWOS
local.indexed.atPUBMED
local.indexed.atSCOPUS
relation.isAuthorOfPublicationeed1d57d-2fc5-4da3-ab50-89ce22ccf43a
relation.isAuthorOfPublication.latestForDiscoveryeed1d57d-2fc5-4da3-ab50-89ce22ccf43a

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