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A neurophysiological approach to the complex organisation of the spine: F-wave duration and the cutaneous silent period in restless legs syndrome

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dc.contributor.authorİŞAK, BARIŞ
dc.contributor.authorsIsak, Baris; Uluc, Kayihan; Salcini, Celal; Agan, Kadriye; Tanridag, Tulin; Us, Onder
dc.date.accessioned2022-03-12T17:50:21Z
dc.date.available2022-03-12T17:50:21Z
dc.date.issued2011
dc.description.abstractObjective: It is generally accepted that F-wave duration (FWD) and the cutaneous silent period (CSP) are influenced by diminished central inhibition. The aim of this study was to diagnose patients of restless legs syndrome (RLS) with the help of FWD and/or CSP parameters. Methods: In all, 24 patients with primary RLS were compared with 31 age-and sex-matched controls. The participants were evaluated based on nerve conduction study (NCS), F-wave parameters (minimum, maximum and mean latency; chronodispersion, persistence and duration; and the ratio of the mean FWD to compound muscle action potential (CMAP) duration), CSP (latency, duration and the ratio of lower-extremity (LE) to upper-extremity (UE) duration that is, silent period ratio (SPR)), the expiration to inspiration ratio (E/I) and sympathetic skin response (SSR). Results: There were not any significant differences in NCS, E/I or SSR between the patients and controls. However, FWD was prolonged (P < 0.0001 for UE and LE) and FWD/CMAP duration was increased in upper and lower extremities (P < 0.001 for UE and P < 0.0001 for LE). Further, CSP latencies in UE (P = 0.030) and LE (P < 0.001) were prolonged, and CSP duration and SPR were significantly reduced in the patient group (P < 0.0001). Conclusions: As both NCS and autonomic test results were in the normal range, abnormalities in FWD and CSP parameters were attributed to the dysfunction of different interneuron groups in the spine. Significance: The use of FWD and CSP could aid in the diagnosis of RLS patients in whom conventional electrophysiological procedures are ineffective. (C) 2010 International Federation of Clinical Neurophysiology. Published by Elsevier Ireland Ltd. All rights reserved.
dc.identifier.doi10.1016/j.clinph.2010.07.005
dc.identifier.eissn1872-8952
dc.identifier.issn1388-2457
dc.identifier.pubmed20724211
dc.identifier.urihttps://hdl.handle.net/11424/230159
dc.identifier.wosWOS:000285995400022
dc.language.isoeng
dc.publisherELSEVIER IRELAND LTD
dc.relation.ispartofCLINICAL NEUROPHYSIOLOGY
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectRestless legs syndrome
dc.subjectF-wave
dc.subjectCutaneous silent period
dc.subjectInterneuron
dc.subjectSURAL NERVE-CONDUCTION
dc.subjectCLINICAL UTILITY
dc.subjectEXCITABILITY
dc.subjectSYSTEM
dc.subjectRAT
dc.subjectMOVEMENTS
dc.subjectDOPAMINE
dc.subjectINTERNEURONS
dc.subjectINHIBITION
dc.subjectNEUROPATHY
dc.titleA neurophysiological approach to the complex organisation of the spine: F-wave duration and the cutaneous silent period in restless legs syndrome
dc.typearticle
dspace.entity.typePublication
local.avesis.idc9a1ddc8-6db2-41d3-839b-e28415096dd4
local.import.packageSS17
local.indexed.atWOS
local.indexed.atSCOPUS
local.indexed.atPUBMED
local.journal.numberofpages8
oaire.citation.endPage390
oaire.citation.issue2
oaire.citation.startPage383
oaire.citation.titleCLINICAL NEUROPHYSIOLOGY
oaire.citation.volume122
relation.isAuthorOfPublication3978eebd-304b-4af3-930c-2db9759c860d
relation.isAuthorOfPublication.latestForDiscovery3978eebd-304b-4af3-930c-2db9759c860d

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