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Psychiatric morbidity of patients with keratoconus: A cross-sectional study

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dc.contributor.authorTOKER, AYŞE EBRU
dc.contributor.authorsYildiz, Mesut; Turhan, Semra Akkaya; Yargi, Berru; Ergun, Serhat; Ornek, Erdem; Baz, Fatih; Toker, Ayse Ebru
dc.date.accessioned2022-03-12T22:58:09Z
dc.date.available2022-03-12T22:58:09Z
dc.date.issued2021
dc.description.abstractBackground: This study aimed to determine the prevalence of psychiatric disorders in patients with keratoconus and the effect of clinical parameters and psychiatric morbidity on quality of life in this patient group. Materials and methods: This cross-sectional study enrolled 94 patients with keratoconus. All patients underwent a complete ophthalmic and psychiatric examination and completed the The National Eye Institute Refractive Error Quality of Life Instrument-42 (NEI-RQL-42), Beck Depression Inventory (BDI) and Beck Anxiety Inventory (BAI) questionnaires. The current diagnosis of psychiatric disorders was determined using the Structured Clinical Interview for DSM-IV (SCID). The impact of disease severity (binocular BCVA >0.4 logMAR, steep K reading >52, and Amsler-Krumeich grades) on vision-related quality of life was also analyzed. Results: The patients? mean age was 23.9 ? 4.8 (range, 18?40) years. Of the 94 participants 35 (37.2%) had a psychiatric diagnosis, 13 (13.8%) had moderate-severe depression and 20 (21.2%) had moderate-severe anxiety according to the BDI and BAI, respectively. The probability of having a psychiatric disorder was higher if the keratoconus was more severe. Patients with a psychiatric diagnosis scored lower on physical functioning, role limitations due to emotional problems, energy/fatigue; emotional well-being, social functioning and pain subscales of the Short Form-36 (SF-36). Having a SCID-1 psychiatric diagnosis and the presence of a psychiatric disorder did not significantly affect NEI-RQL-42 questionnaire scores. Conclusions: There was high psychiatric morbidity among patients with keratoconus. Having a psychiatric disorder was associated with lower QoL as measured using the SF-36.
dc.identifier.doi10.1016/j.jpsychores.2021.110384
dc.identifier.eissn1879-1360
dc.identifier.issn0022-3999
dc.identifier.pubmed33611072
dc.identifier.urihttps://hdl.handle.net/11424/237148
dc.identifier.wosWOS:000635073600009
dc.language.isoeng
dc.publisherPERGAMON-ELSEVIER SCIENCE LTD
dc.relation.ispartofJOURNAL OF PSYCHOSOMATIC RESEARCH
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectCross-sectional study
dc.subjectKeratoconus
dc.subjectPsychiatric morbidity
dc.titlePsychiatric morbidity of patients with keratoconus: A cross-sectional study
dc.typearticle
dspace.entity.typePublication
local.avesis.id63975cb4-d669-4a59-9388-a17ec670b71d
local.import.packageSS17
local.indexed.atWOS
local.indexed.atSCOPUS
local.indexed.atPUBMED
local.journal.articlenumber110384
local.journal.numberofpages6
oaire.citation.titleJOURNAL OF PSYCHOSOMATIC RESEARCH
oaire.citation.volume143
relation.isAuthorOfPublicationf716ff75-0af2-43ed-b219-0a5479d788a2
relation.isAuthorOfPublication.latestForDiscoveryf716ff75-0af2-43ed-b219-0a5479d788a2

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