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Increased arterial stiffness parameters in panic disorder patients in long term treatment period

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dc.contributor.authorSARI, İBRAHİM
dc.contributor.authorsYanartas, Omer; Sunbul, Murat; Senkal, Zeynep; Durmus, Erdal; Kivrak, Tarik; Subasi, Nilufer; Karaer, Gulhan; Ergun, Serhat; Sari, Ibrahim; Sayar, Kemal
dc.date.accessioned2022-03-14T08:13:54Z
dc.date.available2022-03-14T08:13:54Z
dc.date.issued2016-12
dc.description.abstractBackground: The relationship between mental stress and cardiovascular disease has been shown in several studies. Panic disorder (PD) is also associated with cardiovascular disease due to increased risk of myocardial infarction. The aim of this study is to evaluate the association between arterial stiffness parameters and depression/anxiety scores in patients with PD. Methods: The study population consisted of 25 patients with PD and 25 age-sex-matched healthy controls. Depression and anxiety levels were evaluated by Beck Depression Inventory (BDI) and Beck Anxiety Inventory (BAI), respectively. Determination of arterial stiffness parameters was conducted using a Mobil-O-Graph arteriograph system that detected signals from the brachial artery. Results: While baseline characteristics were similar between two groups, BDI and BAI scores were significantly higher in patients with PD (p < 0.005). The pulse wave velocity (PWV) and Augmentation Index (AIx) were also significantly higher in patients with PD (p = 0.001, p = 0.006). There was a moderate correlation between PWV and AIx with BAI scores (r = 0.442, p = 0.001, r = 0.441, p = 0.001). AIx was also positively correlated with BDI scores (r = 0.415, p = 0.03). Conclusion: We demonstrated a significant relationship between arterial stiffness parameters and anxiety/depression scores in patients with PD who receive antidepressant treatment.
dc.identifier.doi10.1186/s12991-016-0102-6
dc.identifier.eissn1744-859X
dc.identifier.pubmed27279893
dc.identifier.urihttps://hdl.handle.net/11424/241168
dc.identifier.wosWOS:000377716100001
dc.language.isoeng
dc.publisherBMC
dc.relation.ispartofANNALS OF GENERAL PSYCHIATRY
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectAnxiety
dc.subjectDepression
dc.subjectArterial stiffness
dc.subjectPulse wave velocity
dc.subjectSymptom severity
dc.subjectCORONARY-HEART-DISEASE
dc.subjectPHOBIC ANXIETY
dc.subjectDEPRESSION
dc.subjectRISK
dc.subjectINVENTORY
dc.titleIncreased arterial stiffness parameters in panic disorder patients in long term treatment period
dc.typearticle
dspace.entity.typePublication
local.avesis.idda3aed69-2397-472b-932a-17aa5cc1fb35
local.import.packageSS16
local.indexed.atWOS
local.indexed.atSCOPUS
local.indexed.atPUBMED
local.journal.articlenumber14
local.journal.numberofpages8
local.journal.quartileQ3
oaire.citation.titleANNALS OF GENERAL PSYCHIATRY
oaire.citation.volume15
relation.isAuthorOfPublication26c97c3b-389c-4a43-9329-8693aa3c3333
relation.isAuthorOfPublication.latestForDiscovery26c97c3b-389c-4a43-9329-8693aa3c3333

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