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Evaluation of infants with HIV-infected mothers and perinatal transmission in Turkey: A single-center experience

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dc.contributor.authorKEPENEKLİ KADAYİFCİ, EDA
dc.contributor.authorsYakut, Nurhayat; Kepenekli, Eda
dc.date.accessioned2022-03-14T09:52:24Z
dc.date.available2022-03-14T09:52:24Z
dc.date.issued2021
dc.description.abstractOBJECTIVE: The most common route of HIV infection in children is through perinatal transmission. In this study, we aimed to evaluate the characteristics of infants with HIV-infected mothers and perinatal HIV transmission. METHODS: We conducted a retrospective, single-center study of HIV-exposed infants in between December 2017 and October 2019 in a Marmara University Pendik Training and Research Hospital. RESULTS: A total of 18 infants were examined. All babies were born by cesarean section, and none of them were breastfed. Seventeen mothers were diagnosed with HIV before pregnancy. These mothers had received antiretroviral therapy (ART) during pregnancy, and their viral loads before delivery were negative. An antiretroviral prophylaxis with oral zidovudine was started in all infants within their 1st day of birth and continued for at least 6 weeks. All infants were tested for their HIV viral load within the first 48 h of birth, with negative results, and 12 infants were tested for anti-HIV antibodies at the 18th month, again with negative results. In this study, we determined that none of the infants had been infected with HIV. CONCLUSION: Our findings highlight the importance of initiating ART for all HIV-infected pregnant women and the importance of protection modalities during pregnancy, delivery, and the postnatal period for the prevention of perinatal transmission of HIV.
dc.identifier.doi10.14744/nci.2021.59013
dc.identifier.issn2148-4902
dc.identifier.pubmed34222804
dc.identifier.urihttps://hdl.handle.net/11424/243462
dc.identifier.wosWOS:000659901800007
dc.language.isoeng
dc.publisherKARE PUBL
dc.relation.ispartofNORTHERN CLINICS OF ISTANBUL
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectChildren
dc.subjectHIV
dc.subjectinfection
dc.subjectperinatal transmission
dc.subjectTurkey
dc.subjectTO-CHILD TRANSMISSION
dc.subjectANTIRETROVIRAL THERAPY
dc.subjectEXPOSED INFANTS
dc.subjectPREVENTION
dc.subjectWOMEN
dc.subjectRATES
dc.titleEvaluation of infants with HIV-infected mothers and perinatal transmission in Turkey: A single-center experience
dc.typearticle
dspace.entity.typePublication
local.avesis.id54b17e5f-c2fb-4736-aa9d-035dbd62fc4f
local.import.packageSS16
local.indexed.atWOS
local.indexed.atPUBMED
local.journal.articlenumber59013
local.journal.numberofpages6
oaire.citation.endPage248
oaire.citation.issue3
oaire.citation.startPage243
oaire.citation.titleNORTHERN CLINICS OF ISTANBUL
oaire.citation.volume8
relation.isAuthorOfPublicationb2936619-4301-4864-bd7e-10de0b997be0
relation.isAuthorOfPublication.latestForDiscoveryb2936619-4301-4864-bd7e-10de0b997be0

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