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The impact of serum FSH and estradiol on postmenopausal osteoporosis related to time since menopause

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dc.contributor.authorYOLDEMİR, AHMET TEVFİK
dc.contributor.authorsYoldemir, Tevfik; Erenus, Mithat; Durmusoglu, Fatih
dc.date.accessioned2022-03-12T18:05:38Z
dc.date.available2022-03-12T18:05:38Z
dc.date.issued2012
dc.description.abstractAim: To determine the impact on osteopenia/osteoporosis of serum follicle-stimulating hormone (FSH), estradiol levels and time since menopause in a group of Turkish postmenopausal women. Methods: Four hundred and thirty-three healthy postmenopausal women seen at the Marmara University Menopause Outpatient Clinic were enrolled for this prospective cohort study. The women were allocated to one of three groups according to the bone mineral density (BMD) of the lumbar vertebrae and total hip, as measured by dual energy X-ray absorptiometry (DEXA). Serum FSH, estradiol levels, age and time since menopause were compared between the groups. Results: The mean serum FSH, LH, estradiol and testosterone levels for women with normal, osteopenic and osteoporotic BMD at lumbar vertrebra L1-L4 and total hip were comparable. Time since menopause had a stronger predictive value for low BMD (osteopenia or osteoporosis) in the lumbar and hip areas than did serum FSH or estradiol levels. Conclusions: Our study showed that neither FSH nor E2 has a strong impact on postmenopausal BMD. However it appears that time since menopause has a weak non-significant association with postmenopausal osteopenia and osteoporosis.
dc.identifier.doi10.3109/09513590.2012.683066
dc.identifier.eissn1473-0766
dc.identifier.issn0951-3590
dc.identifier.pubmed22731753
dc.identifier.urihttps://hdl.handle.net/11424/230737
dc.identifier.wosWOS:000309938700013
dc.language.isoeng
dc.publisherTAYLOR & FRANCIS LTD
dc.relation.ispartofGYNECOLOGICAL ENDOCRINOLOGY
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectFSH
dc.subjectestradiol
dc.subjectosteoporosis
dc.subjecttime since menopause
dc.subjectBONE-MINERAL DENSITY
dc.subjectFOLLICLE-STIMULATING-HORMONE
dc.subjectSEX STEROIDS
dc.subjectWOMEN
dc.subjectESTROGEN
dc.subjectAGE
dc.subjectDETERMINANTS
dc.subjectAMENORRHEA
dc.subjectCELLS
dc.subjectMASS
dc.titleThe impact of serum FSH and estradiol on postmenopausal osteoporosis related to time since menopause
dc.typearticle
dspace.entity.typePublication
local.avesis.id5721f601-258a-4082-b36a-5586af898cd8
local.import.packageSS17
local.indexed.atWOS
local.indexed.atSCOPUS
local.indexed.atPUBMED
local.journal.numberofpages5
oaire.citation.endPage888
oaire.citation.issue11
oaire.citation.startPage884
oaire.citation.titleGYNECOLOGICAL ENDOCRINOLOGY
oaire.citation.volume28
relation.isAuthorOfPublicationa83f8663-e08c-4cde-a28b-fbd444a689e0
relation.isAuthorOfPublication.latestForDiscoverya83f8663-e08c-4cde-a28b-fbd444a689e0

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