Publication:
Evaluation of Cardiac Function by Two-Dimensional Speckle Tracking Echocardiography in Ulcerative Colitis Patients

Simple item page
dc.contributor.authorÇİNÇİN, AHMET ALTUĞ
dc.contributor.authorsCincin, Altug; Sunbul, Murat; Kivrak, Tarik; Atas, Halil; Sari, Ibrahim; Tigen, Kursat; Kani, Tarik; Akin, Hakan; Imeryuz, Nese; Basaran, Yelda
dc.date.accessioned2022-03-13T12:44:38Z
dc.date.available2022-03-13T12:44:38Z
dc.date.issued2014
dc.description.abstractPurpose Although ulcerative colitis (UC) shows obvious similarities with other autoimmune diseases, cardiac consequences have not adequately introduced. The aim of our study was to evaluate left ventricular (LV) function in UC patients by using novel echocardiographic parameters. Results Forty-five UC patients (mean age 37, 18 female) and 90 age-and sex-matched healthy volunteers (mean age 40, 38 female) included in the study. The mean disease activity score according to partial Mayo score was 2.16 +/- 2.13. Mean global longitudinal strain (GLS) and global longitudinal strain rate (GLSR) measurements were significantly lower (-21.16 +/- 2.71 vs. -23.36 +/- 3.34; p < 0.001 and -1.33 +/- 0.24 vs. -1.43 +/- 0.24; p = 0.037, respectively), whereas global circumferential (-22.67 +/- 3.66 vs. -23.37 +/- 3.99; p = 0.140) and global radial strain (43.07 +/- 8.58 vs. 44.12 +/- 9.32; p = 0.545) measurements of the LV were similar in patients with UC compared with controls. The correlation coefficient (r) between GLS and partial Mayo score was -0.578 (p < 0.001). Conclusion Our study suggests that systolic cardiac deformation values are impaired in UC patients. Reduced GLS and GLSR might be an early indicator of cardiac involvement in this population.
dc.identifier.doi10.1007/s10620-014-3274-4
dc.identifier.eissn1573-2568
dc.identifier.issn0163-2116
dc.identifier.pubmed25023227
dc.identifier.urihttps://hdl.handle.net/11424/237602
dc.identifier.wosWOS:000345322100020
dc.language.isoeng
dc.publisherSPRINGER
dc.relation.ispartofDIGESTIVE DISEASES AND SCIENCES
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectEchocardiography
dc.subjectUlcerative colitis
dc.subjectInflammatory bowel disease
dc.subjectSpeckle
dc.subjectStrain
dc.subjectINFLAMMATORY-BOWEL-DISEASE
dc.subjectLEFT-VENTRICULAR DYSFUNCTION
dc.subjectGLOBAL LONGITUDINAL STRAIN
dc.subjectMAGNETIC-RESONANCE
dc.subjectSYSTEMIC-SCLEROSIS
dc.subjectDIABETES-MELLITUS
dc.subjectHEART-FAILURE
dc.subjectFOLLOW-UP
dc.subjectDIAGNOSIS
dc.subjectTHERAPY
dc.titleEvaluation of Cardiac Function by Two-Dimensional Speckle Tracking Echocardiography in Ulcerative Colitis Patients
dc.typearticle
dspace.entity.typePublication
local.avesis.id0de1b661-7737-4ced-a97b-7926880775bb
local.import.packageSS17
local.indexed.atWOS
local.indexed.atSCOPUS
local.indexed.atPUBMED
local.journal.numberofpages8
oaire.citation.endPage3011
oaire.citation.issue12
oaire.citation.startPage3004
oaire.citation.titleDIGESTIVE DISEASES AND SCIENCES
oaire.citation.volume59
relation.isAuthorOfPublication54255a29-54c0-43de-8bc5-39d805d1296a
relation.isAuthorOfPublication.latestForDiscovery54255a29-54c0-43de-8bc5-39d805d1296a

Files

Collections

Research Outputs