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Does cardiovascular risk vary according to the criteria for a diagnosis of polycystic ovary syndrome?

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dc.contributor.authorYOLDEMİR, AHMET TEVFİK
dc.contributor.authorsRamoglu, Sedef; Yoldemir, Tevfik; Atasayan, Kemal; Yavuz, Dilek Gogas
dc.date.accessioned2022-03-12T20:30:39Z
dc.date.available2022-03-12T20:30:39Z
dc.date.issued2017
dc.description.abstractAimThe risk of cardiovascular disease is higher in women with polycystic ovary syndrome (PCOS) compared to healthy individuals. Chronic inflammation, insulin resistance, hyperandrogenemia, hyperlipidemia and increased oxidative stress are known to have a role in the formation of atherosclerosis and cardiovascular disease. The aim of our study was to evaluate if cardiovascular risk varied according to different PCOS criteria, using carotid intima-media thickness (CIMT), which is an important marker of major cardiovascular events in the later stages of life. MethodsThe study group included 52 women aged 18-35 diagnosed with PCOS, and the control group comprised 45 age-matched healthy women. Body mass index, CIMT, fasting serum glucose and insulin levels and hormonal and lipid profiles were compared between the groups. ResultsThere was no significant difference in CIMT levels between the groups. The CIMT levels in the PCOS group did not differ whether hyperandrogenism, polycystic ovary-like appearance on ultrasound or oligo/anovulation status were present or not. Furthermore, when all cases were divided into subgroups according to BMI values, the CIMT values were similar between the groups. ConclusionBecause PCOS and atherosclerosis both have a complex nature, it is likely that the evaluation of CIMT alone may not be sufficient to determine endothelial dysfunction in a reproductive age group.
dc.identifier.doi10.1111/jog.13455
dc.identifier.eissn1447-0756
dc.identifier.issn1341-8076
dc.identifier.pubmed28892255
dc.identifier.urihttps://hdl.handle.net/11424/234196
dc.identifier.wosWOS:000418412200007
dc.language.isoeng
dc.publisherWILEY
dc.relation.ispartofJOURNAL OF OBSTETRICS AND GYNAECOLOGY RESEARCH
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectbody mass index
dc.subjectcardiovascular risk
dc.subjectcarotid intima-media thickness
dc.subjectpolycystic ovary syndrome
dc.subjectINTIMA-MEDIA THICKNESS
dc.subjectPREMATURE CAROTID ATHEROSCLEROSIS
dc.subjectYOUNG-WOMEN
dc.subjectARTERIAL STIFFNESS
dc.subjectSUBCLINICAL ATHEROSCLEROSIS
dc.subjectINSULIN-RESISTANCE
dc.subjectVASCULAR FUNCTION
dc.subjectANDROGEN EXCESS
dc.subjectSYNDROME PCOS
dc.subjectDISEASE RISK
dc.titleDoes cardiovascular risk vary according to the criteria for a diagnosis of polycystic ovary syndrome?
dc.typearticle
dspace.entity.typePublication
local.avesis.id34dae21b-0aad-4a7c-aebf-136ed6d2fddb
local.import.packageSS17
local.indexed.atWOS
local.indexed.atSCOPUS
local.indexed.atPUBMED
local.journal.numberofpages7
local.journal.quartileQ4
oaire.citation.endPage1854
oaire.citation.issue12
oaire.citation.startPage1848
oaire.citation.titleJOURNAL OF OBSTETRICS AND GYNAECOLOGY RESEARCH
oaire.citation.volume43
relation.isAuthorOfPublicationa83f8663-e08c-4cde-a28b-fbd444a689e0
relation.isAuthorOfPublication.latestForDiscoverya83f8663-e08c-4cde-a28b-fbd444a689e0

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