Publication:
Synthesis, Complexation, and Biological Activity Studies of 4-Aminomethyl-7,8-dihydroxy Coumarines and Their Crown Ether Derivatives

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Date

2010

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WILEY

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Abstract

The article focuses synthesis of novel 4-aminomethyl-7,8-dihydroxy coumarins and their crown ether derivatives. The purified novel coumarins and their crown ether derivatives were identified by H-1 NMR, C-13 NMR, mass spectrometry and elemental analysis. The 1:1 binding constants of Ca2+, Mg2+, Fe2+, Zn2+, Ni2+, Cd2+, Co2+, and Mn2+ ions at 25 degrees C +/- 0.1 with the 4-aminomethyl-7,8-dihydroxy coumarins and their crown ether derivatives estimated using extraction procedure with Inductively Coupled Plasma-Atomic Emission Spectroscopy in dichloromethane/water membrane systems. Synthesized compounds were investigated for complexation and biological activity properties. Best results in biological activity studies were observed for antioxidant activity.

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EXCITED-STATE PROPERTIES, SOLVENT-EXTRACTION, (COUMARIN-4-YL)METHYL DERIVATIVES, FUNDAMENTAL EQUILIBRIA, DEACTIVATION BEHAVIOR, CYCLIC POLYETHERS, METAL PICRATES, ION-PAIR, 18-CROWN-6, PHOTOCLEAVAGE

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https://hdl.handle.net/11424/230031

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