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Choroidal vascularity index as an activity criterion and a treatment response measure in chronic central serous chorioretinopathy

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dc.contributor.authorŞAHİN, ÖZLEM
dc.contributor.authorSEVİK, MEHMET ORKUN
dc.contributor.authorÇAM, FURKAN
dc.contributor.authorDERİCİOĞLU, VOLKAN
dc.contributor.authorsSEVİK M. O., Aykut A., ÇAM F., DERİCİOĞLU V., ŞAHİN Ö.
dc.date.accessioned2023-08-21T10:33:01Z
dc.date.available2023-08-21T10:33:01Z
dc.date.issued2023-01-01
dc.description.abstractPurpose: This study aimed to evaluate the choroidal vascularity index (CVI) as an activity criterion in chronic central serous chorioretinopathy (CSC) and as a measure of treatment response after full-dose-full-fluence photodynamic therapy (fd-ff-PDT). Methods: This fellow-eye-controlled, retrospective cohort study included 23 patients with unilateral chronic CSC treated with fd-ff-PDT (6 mg/m2; 50 μcm2; 83 s). Subfoveal choroidal thickness (SFCT, μm) and CVI (%) of the affected and fellow eyes at baseline as well as at 1, 3 and 6 months after fd-ff-PDT were compared. Results: The patients\" mean age was 43.4 ± 7.3 years, and 18 (78.3%) were male. CVI was comparable between the affected and fellow eyes at baseline (66.09 ± 1.56 vs. 65.84 ± 1.57, p = 0.59). However, it became significantly lower in the affected eyes 1 (64.45 ± 1.68 vs. 65.87 ± 1.19, p = 0.002), 3 (64.21 ± 2.08 vs. 65.71 ± 1.59, p = 0.009) and 6 (64.47 ± 2.19 vs. 65.62 ± 1.52, p = 0.045) months after fd-ff-PDT. The mean SFCT and the mean CVI were significantly decreased in the affected eyes at all follow-up visits compared with baseline after fd-ff-PDT (p < 0.001). Conclusion: At baseline, CVI was comparable between affected and fellow eyes. Therefore, its use as an activity criterion in chronic CSC patients is questionable. However, it was significantly decreased in fd-ff-PDT-treated eyes, supporting its role as a measure of treatment response in chronic CSC.
dc.identifier.citationSEVİK M. O., Aykut A., ÇAM F., DERİCİOĞLU V., ŞAHİN Ö., "Choroidal vascularity index as an activity criterion and a treatment response measure in chronic central serous chorioretinopathy", Ophthalmic and Physiological Optics, 2023
dc.identifier.doi10.1111/opo.13187
dc.identifier.issn0275-5408
dc.identifier.urihttps://onlinelibrary.wiley.com/doi/epdf/10.1111/opo.13187
dc.identifier.urihttps://hdl.handle.net/11424/292733
dc.language.isoeng
dc.relation.ispartofOphthalmic and Physiological Optics
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectTıp
dc.subjectCerrahi Tıp Bilimleri
dc.subjectGöz Hastalıkları ve Cerrahisi
dc.subjectYaşam Bilimleri
dc.subjectSağlık Bilimleri
dc.subjectTemel Bilimler
dc.subjectMedicine
dc.subjectSurgery Medicine Sciences
dc.subjectEye Diseases and Surgery
dc.subjectLife Sciences
dc.subjectHealth Sciences
dc.subjectNatural Sciences
dc.subjectKlinik Tıp (MED)
dc.subjectYaşam Bilimleri (LIFE)
dc.subjectKlinik Tıp
dc.subjectSinirbilim ve Davranış
dc.subjectGÖZ HASTALIKLARI
dc.subjectSİNİR BİLİMİ
dc.subjectClinical Medicine (MED)
dc.subjectLife Sciences (LIFE)
dc.subjectCLINICAL MEDICINE
dc.subjectNEUROSCIENCE & BEHAVIOR
dc.subjectOPHTHALMOLOGY
dc.subjectNEUROSCIENCES
dc.subjectOftalmoloji
dc.subjectOptometri
dc.subjectDuyusal Sistemler
dc.subjectOphthalmology
dc.subjectOptometry
dc.subjectSensory Systems
dc.subjectcentral serous chorioretinopathy
dc.subjectchoroidal vascularity index
dc.subjectsubfoveal choroidal thickness
dc.titleChoroidal vascularity index as an activity criterion and a treatment response measure in chronic central serous chorioretinopathy
dc.typearticle
dspace.entity.typePublication
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local.indexed.atPUBMED
local.indexed.atSCOPUS
local.indexed.atWOS
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