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Investigation of oral and fecal colonization with candida species and associated factors in human immunodeficiency virus-infected children in Turkey

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dc.contributor.authorKEPENEKLİ KADAYİFCİ, EDA
dc.contributor.authorsBilgi E. A., Genc G. E., Kara M., KEPENEKLİ KADAYİFCİ E., Torun S. H., BAYDEMİR C., Somer A., Agacfidan A., Erturan Z.
dc.date.accessioned2023-04-24T08:15:41Z
dc.date.available2023-04-24T08:15:41Z
dc.date.issued2023-03-01
dc.description.abstractObjective The risk of endogenous infections in human immunodeficiency virus (HIV)-infected individuals increases with Candida species colonized in mouth and intestinal areas. The predisposing factors for colonization and the prevalence of different Candida spp. in HIV-infected Turkish children remain unknown. This study aimed to determine the colonization frequency and risk factors of colonization with Candida species in oral and fecal samples of HIV-infected pediatric patients in relation to a control group.Methods Oral and feces samples of 22 HIV-infected and 52 healthy children were plated onto CHROMagar and CHROM-Pal-agar. Yeasts were identified by conventional methods, and strains with insufficient identification were identified by molecular techniques.Results Candida spp. were detected in oral/fecal samples of 50%/68.2% HIV-infected and 36.5%/73.1% healthy children. The most common species was Candida albicans in oral and fecal samples of HIV-infected (31.8 and 31.8%) and healthy (26.9 and 48.1%) children. The most frequently non-albicans species in oral samples was Candida dubliniensis (18.2%) in HIV-infected children and Candida parapsilosis (3.8%) in healthy children. In feces samples, C. parapsilosis , Candida glabrata , and Candida krusei were most frequent (13.6%, each) in HIV-infected patients, and Candida kefyr (11.5%) was most frequent in controls. There was a significant association between oral C. dubliniensis colonization and HIV infection ( p = 0.006). Yeast carriage was not associated with gender and viral load in HIV-infected patients.Conclusion The isolation of C. dubliniensis from oral and fecal samples of pediatric HIV patients was done for the first time in Turkey in the present study. Additional studies are needed to clarify the factors associated with oral and fecal Candida colonization in these children.
dc.identifier.citationBilgi E. A., Genc G. E., Kara M., KEPENEKLİ KADAYİFCİ E., Torun S. H., BAYDEMİR C., Somer A., Agacfidan A., Erturan Z., "Investigation of Oral and Fecal Colonization with Candida Species and Associated Factors in Human Immunodeficiency Virus-Infected Children in Turkey", JOURNAL OF PEDIATRIC INFECTIOUS DISEASES, 2023
dc.identifier.doi10.1055/s-0043-1767737
dc.identifier.issn1305-7707
dc.identifier.urihttps://avesis.marmara.edu.tr/api/publication/d22daa73-cad1-4f56-88f7-cfaf38d0ebd7/file
dc.identifier.urihttps://hdl.handle.net/11424/288859
dc.language.isoeng
dc.relation.ispartofJOURNAL OF PEDIATRIC INFECTIOUS DISEASES
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectTıp
dc.subjectDahili Tıp Bilimleri
dc.subjectÇocuk Sağlığı ve Hastalıkları
dc.subjectYaşam Bilimleri
dc.subjectSağlık Bilimleri
dc.subjectTemel Bilimler
dc.subjectMedicine
dc.subjectInternal Medicine Sciences
dc.subjectChild Health and Diseases
dc.subjectLife Sciences
dc.subjectHealth Sciences
dc.subjectNatural Sciences
dc.subjectBULAŞICI HASTALIKLAR
dc.subjectİmmünoloji
dc.subjectYaşam Bilimleri (LIFE)
dc.subjectPEDİATRİ
dc.subjectKlinik Tıp
dc.subjectKlinik Tıp (MED)
dc.subjectINFECTIOUS DISEASES
dc.subjectIMMUNOLOGY
dc.subjectLife Sciences (LIFE)
dc.subjectPEDIATRICS
dc.subjectCLINICAL MEDICINE
dc.subjectClinical Medicine (MED)
dc.subjectPediatri
dc.subjectPediatri, Perinatoloji ve Çocuk Sağlığı
dc.subjectBulaşıcı hastalıklar
dc.subjectGenel İmmünoloji ve Mikrobiyoloji
dc.subjectPediatrics
dc.subjectPediatrics, Perinatology and Child Health
dc.subjectInfectious Diseases
dc.subjectImmunology
dc.subjectGeneral Immunology and Microbiology
dc.subjectHIV
dc.subjectchildren
dc.subjectCandida
dc.subjectoral colonization
dc.subjectfecal colonization
dc.subjectACTIVE ANTIRETROVIRAL THERAPY
dc.subjectRIO-DE-JANEIRO
dc.subjectHEALTHY-CHILDREN
dc.subjectIMMUNOGLOBULIN-A
dc.subjectHIV PATIENTS
dc.subjectCARRIAGE
dc.subjectYEAST
dc.subjectRINSE
dc.subjectMANIFESTATIONS
dc.subjectDUBLINIENSIS
dc.subjectHIV
dc.subjectchildren
dc.subjectCandida
dc.subjectoral colonization
dc.subjectfecal colonization
dc.titleInvestigation of oral and fecal colonization with candida species and associated factors in human immunodeficiency virus-infected children in Turkey
dc.typearticle
dspace.entity.typePublication
local.avesis.idd22daa73-cad1-4f56-88f7-cfaf38d0ebd7
local.indexed.atWOS
relation.isAuthorOfPublicationb2936619-4301-4864-bd7e-10de0b997be0
relation.isAuthorOfPublication.latestForDiscoveryb2936619-4301-4864-bd7e-10de0b997be0

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