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Thyroid disease in the perimenopause and postmenopause period

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dc.contributor.authorYOLDEMİR, AHMET TEVFİK
dc.contributor.authorsUygur, M. M.; Yoldemir, T.; Yavuz, D. G.
dc.date.accessioned2022-03-10T15:25:27Z
dc.date.available2022-03-10T15:25:27Z
dc.date.issued2018
dc.description.abstractThe interpretation of thyroid function tests should be cautiously made during the perimenopause and postmenopause period bearing in mind that physiologic changes do exist in this group of women in terms of secretion and metabolism of thyrotropin and thyroid hormones. Moreover the incidence of thyroid disorders increases in postmenopausal and elderly women. There is no consensus for screening postmenopausal women even though there is well-known evidence about the effect of thyroid status on cognitive function, cardiovascular risk, bone turnover, and longevity. The diagnosis of any thyroid disorder is challenging in these patients because the symptoms are more subtle and attributed to menopausal symptoms. Management requires more attention in this population than that of younger groups, because high doses of L-thyroxine can lead to cardiac complications and increased bone turnover. Furthermore radio-iodine is preferred in treatment of hyperthyroidism in older patients. The risk of nodular thyroid disease and thyroid cancers increases in this group. Although the diagnostic approach is the same as for young patients, the risk of surgery is high and disease prognosis is worse. Women with any form of thyroid disease should be treated according to the current guidelines. Decision for menopausal hormonal therapy should be individualized regardless of the concomitant presence of thyroid disorders.
dc.identifier.doi10.1080/13697137.2018.1514004
dc.identifier.eissn1473-0804
dc.identifier.issn1369-7137
dc.identifier.pubmed30296186
dc.identifier.urihttps://hdl.handle.net/11424/220252
dc.identifier.wosWOS:000453060600006
dc.language.isoeng
dc.publisherTAYLOR & FRANCIS LTD
dc.relation.ispartofCLIMACTERIC
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectHypothyroidism
dc.subjecthyperthyroidism
dc.subjectthyroid cancer
dc.subjectmenopause
dc.subjectCORONARY-HEART-DISEASE
dc.subjectSERUM THYROTROPIN
dc.subjectSUBCLINICAL HYPERTHYROIDISM
dc.subjectCARDIOVASCULAR EVENTS
dc.subjectCOGNITIVE FUNCTION
dc.subjectFOLLOW-UP
dc.subjectASSOCIATION GUIDELINES
dc.subjectSTIMULATING HORMONE
dc.subjectPREDICTIVE-VALUE
dc.subjectNATURAL-HISTORY
dc.titleThyroid disease in the perimenopause and postmenopause period
dc.typereview
dspace.entity.typePublication
local.avesis.id7b44545a-0628-4477-89ff-e534d9e82bcc
local.import.packageSS5
local.indexed.atWOS
local.indexed.atSCOPUS
local.indexed.atPUBMED
local.journal.numberofpages7
local.journal.quartileQ2
oaire.citation.endPage548
oaire.citation.issue6
oaire.citation.startPage542
oaire.citation.titleCLIMACTERIC
oaire.citation.volume21
relation.isAuthorOfPublicationa83f8663-e08c-4cde-a28b-fbd444a689e0
relation.isAuthorOfPublication.latestForDiscoverya83f8663-e08c-4cde-a28b-fbd444a689e0

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