Publication:
3D Printed Polycaprolactone/Gelatin/Bacterial Cellulose/Hydroxyapatite Composite Scaffold for Bone Tissue Engineering

dc.contributor.authorŞAHİN, ALİ
dc.contributor.authorsCakmak, Abdullah M.; Unal, Semra; Sahin, Ali; Oktar, Faik N.; Sengor, Mustafa; Ekren, Nazmi; Gunduz, Oguzhan; Kalaskar, Deepak M.
dc.date.accessioned2022-03-14T09:23:44Z
dc.date.available2022-03-14T09:23:44Z
dc.date.issued2020-08-29
dc.description.abstractThree-dimensional (3D) printing application is a promising method for bone tissue engineering. For enhanced bone tissue regeneration, it is essential to have printable composite materials with appealing properties such as construct porous, mechanical strength, thermal properties, controlled degradation rates, and the presence of bioactive materials. In this study, polycaprolactone (PCL), gelatin (GEL), bacterial cellulose (BC), and different hydroxyapatite (HA) concentrations were used to fabricate a novel PCL/GEL/BC/HA composite scaffold using 3D printing method for bone tissue engineering applications. Pore structure, mechanical, thermal, and chemical analyses were evaluated. 3D scaffolds with an ideal pore size (similar to 300 mu m) for use in bone tissue engineering were generated. The addition of both bacterial cellulose (BC) and hydroxyapatite (HA) into PCL/GEL scaffold increased cell proliferation and attachment. PCL/GEL/BC/HA composite scaffolds provide a potential for bone tissue engineering applications.
dc.identifier.doi10.3390/polym12091962
dc.identifier.eissn2073-4360
dc.identifier.pubmed32872547
dc.identifier.urihttps://hdl.handle.net/11424/243063
dc.identifier.wosWOS:000580396100001
dc.language.isoeng
dc.publisherMDPI
dc.relation.ispartofPOLYMERS
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectbacterial cellulose
dc.subjectgelatin
dc.subjectpolycaprolactone
dc.subjecthydroxyapatite
dc.subject3D printing
dc.subjectbone tissue engineering
dc.subjectBACTERIAL CELLULOSE
dc.subjectPOLYCAPROLACTONE SCAFFOLDS
dc.subjectGELATIN
dc.subjectFABRICATION
dc.subjectDEPOSITION
dc.subjectFIBERS
dc.title3D Printed Polycaprolactone/Gelatin/Bacterial Cellulose/Hydroxyapatite Composite Scaffold for Bone Tissue Engineering
dc.typearticle
dspace.entity.typePublication
local.avesis.id16d4d4fa-8c80-4868-9820-ce88da8002e4
local.import.packageSS16
local.indexed.atWOS
local.indexed.atSCOPUS
local.indexed.atPUBMED
local.journal.articlenumber1962
local.journal.numberofpages14
local.journal.quartileQ1
oaire.citation.issue9
oaire.citation.titlePOLYMERS
oaire.citation.volume12
relation.isAuthorOfPublicationdda71138-8ce4-4265-89b2-73bc94786a4f
relation.isAuthorOfPublication.latestForDiscoverydda71138-8ce4-4265-89b2-73bc94786a4f

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