Publication:
Neutrophil and lymphocyte ratio in craniocervical artery dissection and prognostic correlations of the blood biomarkers

dc.contributor.authorAKDENİZ, ESRA
dc.contributor.authorÖMERCİKOĞLU ÖZDEN, HATİCE
dc.contributor.authorBALTACIOĞLU, FEYYAZ
dc.contributor.authorMİDİ, İPEK
dc.contributor.authorsMİDİ İ., Ciftci A. C., Ekincikli B. T., AKDENİZ E., ÖMERCİKOĞLU ÖZDEN H., Babashova L., BALTACIOĞLU F.
dc.date.accessioned2023-05-02T08:15:52Z
dc.date.available2023-05-02T08:15:52Z
dc.date.issued2022-03-01
dc.description.abstractBackground & Objective: The aim of this study was to investigate the relationship of neutrophil to lymphocyte ratio (NLR) and other blood cells markers in craniocervical artery dissection patients and the dynamic changes of these biomarkers during the disease course, and effects on prognosis of the patients. Method: Cranial MR imaging, cranial and cervical MR angiography and DSA were examined, and diffusion weighted imaging (DWI) was performed to show the acute lesion(s). Results: Forty-six patients with craniocervical artery dissection were included in this study; they had a mean age of 42 years. Almost 60% of the patients (n=27) were admitted during acute state. Almost 2/3 of cases had extracranial dissection (n=31) and nearly 40% of the patients (n=18) had trauma. Neutrophil to lymphocyte ratio (NLR) was observed to be higher in the acute phase of the disease while the ratio decreased in the chronic phase. Low hemoglobin, high lymphocyte and a high NLR were found to have a negative correlation with the National Institutes of Health Stroke Scale (NIHSS). Conclusion: Elevation of neutrophil was higher in acute craniocervical artery dissection as a marker of acute inflammatory response. High NLR, low hemoglobin and high eosinophil levels were associated with worse prognosis and functional outcomes.
dc.identifier.citationMİDİ İ., Ciftci A. C., Ekincikli B. T., AKDENİZ E., ÖMERCİKOĞLU ÖZDEN H., Babashova L., BALTACIOĞLU F., "Neutrophil and lymphocyte ratio in craniocervical artery dissection and prognostic correlations of the blood biomarkers", NEUROLOGY ASIA, cilt.27, sa.1, ss.35-44, 2022
dc.identifier.doi10.54029/2022svn
dc.identifier.endpage44
dc.identifier.issn1823-6138
dc.identifier.issue1
dc.identifier.startpage35
dc.identifier.urihttps://www.scopus.com/record/display.uri?eid=2-s2.0-85128386225&origin=resultslist&sort=plf-f&src=s&st1=Neutrophil+and+lymphocyte+ratio+in+craniocervical+artery+dissection+and+prognostic+correlations+of+the+blood+biomarkers&sid=780c51be669382b8286e83ecb7fda421&sot=b&sdt=b&sl=134&s=TITLE-ABS-KEY%28Neutrophil+and+lymphocyte+ratio+in+craniocervical+artery+dissection+and+prognostic+correlations+of+the+blood+biomarkers%29&relpos=0&citeCnt=0&searchTerm=
dc.identifier.urihttps://hdl.handle.net/11424/289027
dc.identifier.volume27
dc.language.isoeng
dc.relation.ispartofNEUROLOGY ASIA
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectTıp
dc.subjectSağlık Bilimleri
dc.subjectDahili Tıp Bilimleri
dc.subjectNöroloji
dc.subjectMedicine
dc.subjectHealth Sciences
dc.subjectInternal Medicine Sciences
dc.subjectNeurology
dc.subjectKLİNİK NÖROLOJİ
dc.subjectKlinik Tıp
dc.subjectKlinik Tıp (MED)
dc.subjectCLINICAL NEUROLOGY
dc.subjectCLINICAL MEDICINE
dc.subjectClinical Medicine (MED)
dc.subjectNeurology (clinical)
dc.subjectLife Sciences
dc.subjectCraniocervical artery dissection
dc.subjectneutrophil to lymphocyte ratio (NLR)
dc.subjectprognosis
dc.subjectISCHEMIC-STROKE
dc.subjectTO-LYMPHOCYTE
dc.subjectPREDICTOR
dc.subjectINFLAMMATION
dc.subjectASSOCIATION
dc.subjectCraniocervical artery dissection
dc.subjectneutrophil to lymphocyte ratio (NLR)
dc.subjectprognosis
dc.titleNeutrophil and lymphocyte ratio in craniocervical artery dissection and prognostic correlations of the blood biomarkers
dc.typearticle
dspace.entity.typePublication
local.avesis.id6811f01e-3424-4a57-8cfa-8565ffdd7bd7
local.indexed.atWOS
local.indexed.atSCOPUS
relation.isAuthorOfPublication247544af-fbb8-4147-a94d-b693a76513de
relation.isAuthorOfPublicationde8add41-7d97-4f8e-bc16-39ff18590bfc
relation.isAuthorOfPublication14b6381a-4f6e-4ff9-92f6-842a481bc163
relation.isAuthorOfPublicationa436ba9b-29cc-4170-b37f-ba8e767e9c59
relation.isAuthorOfPublication.latestForDiscovery247544af-fbb8-4147-a94d-b693a76513de

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