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A standardized sonographic analysis of nails in psoriatic arthritis and healthy controls: Feasibility, reliability, diagnostic performance, and demographic and clinical associations

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dc.contributor.authorGEZER, HALİSE HANDE
dc.contributor.authorsKasman, Sevtap Acer; Gezer, Halise Hande; Baklacioglu, Hatice Sule; Gursoy, Didem Erdem; Duruoz, Mehmet Tuncay
dc.date.accessioned2022-03-12T22:57:41Z
dc.date.available2022-03-12T22:57:41Z
dc.date.issued2021
dc.description.abstractObjectives: Subunits of the nail can be evaluated by nail ultrasonography (NUSG). The purposes of this study are to document NUSG properties (both nail-based and participant-based evaluations) in patients with psoriatic arthritis (PsA) and healthy controls and to explore the final scorings. Methods: After the literature review and a pilot study, a consensus was reached to evaluate 12 nails and 5 parameters by NUSG: nail plate impairment (NPI), nail plate thickness (NPT), nail bed thickness (NBT), nail thickness (NT), and Doppler activity (DA); further, scorings for each parameter (NPIs, NPTs, NBTs, NTs, and DAs) were calculated. Group comparisons and diagnostic performances (with ROC curve analysis) were applied to both parameters and scorings. Final scorings to predict PsA diagnosis among the NUSG scorings were reached by regression analysis. Feasibility, reliability, and clinical associations of the scores were also performed. Results: Sixty-four patients with PsA and 26 controls (3240 baseline images) were assessed. The most affected nails, PsA/control comparisons, and the ROC analysis varied among the nails, within the higher values of PsA; therefore, 12 nails remained in the scorings. Participant-based scorings showed better content and diagnostic performances than the nail-based. Diagnostic performances, feasibility, reliability, and regression analysis of the scorings documented that NPIs, NTs, and DAs were the best. Some demographics, employee status, hemoglobin, and disease activity of the participants were associated with them. Conclusions: The NUSG Index (NUSGI) including NPIs, NTs, and DAs is a feasible, reliable, and discriminative method to predict PsA diagnosis, with its rich content. (C) 2021 Societe francaise de rhumatologie. Published by Elsevier Masson SAS. All rights reserved.
dc.identifier.doi10.1016/j.jbspin.2021.105197
dc.identifier.eissn1778-7254
dc.identifier.issn1297-319X
dc.identifier.pubmed33901660
dc.identifier.urihttps://hdl.handle.net/11424/237081
dc.identifier.wosWOS:000710089000022
dc.language.isoeng
dc.publisherELSEVIER FRANCE-EDITIONS SCIENTIFIQUES MEDICALES ELSEVIER
dc.relation.ispartofJOINT BONE SPINE
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectNail ultrasound
dc.subjectPsoriatic arthritis
dc.subjectNail ultrasonography index
dc.subjectNail plate
dc.subjectNail thickness
dc.subjectDiagnostic
dc.subjectHIGH-FREQUENCY SONOGRAPHY
dc.subjectJOINT DISEASE
dc.subjectULTRASOUND
dc.subjectULTRASONOGRAPHY
dc.titleA standardized sonographic analysis of nails in psoriatic arthritis and healthy controls: Feasibility, reliability, diagnostic performance, and demographic and clinical associations
dc.typearticle
dspace.entity.typePublication
local.avesis.id8fda4480-7f68-4658-ba57-b1a7ea4c4dec
local.import.packageSS17
local.indexed.atWOS
local.indexed.atSCOPUS
local.indexed.atPUBMED
local.journal.articlenumber105197
local.journal.numberofpages6
oaire.citation.issue5
oaire.citation.titleJOINT BONE SPINE
oaire.citation.volume88
relation.isAuthorOfPublication448ac4c5-d06d-4874-9734-5bc76f6eb2fe
relation.isAuthorOfPublication.latestForDiscovery448ac4c5-d06d-4874-9734-5bc76f6eb2fe

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