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ASSESSMENT OF SYMPTOMATIC DIABETIC PATIENTS WITH NORMAL NERVE CONDUCTION STUDIES: UTILITY OF CUTANEOUS SILENT PERIODS AND AUTONOMIC TESTS

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dc.contributor.authorİŞAK, BARIŞ
dc.contributor.authorsKoytak, Pinar Kahraman; Isak, Baris; Borucu, Deniz; Uluc, Kayihan; Tanridag, Tulin; Us, Onder
dc.date.accessioned2022-03-12T17:50:54Z
dc.date.available2022-03-12T17:50:54Z
dc.date.issued2011
dc.description.abstractEstablished electrophysiological methods have limited clinical utility in the diagnosis of small-fiber neuropathy (SFN). In this study, diabetic patients with clinically diagnosed SFN were evaluated with autonomic tests and cutaneous silent periods (CSPs). Thirty-one diabetic patients with clinically suspected SFN and normal nerve conduction studies were compared with 30 controls. In the upper extremities (UE), the CSP parameters did not differ statistically between the patient and control groups, whereas, in the lower extremities (LE), patients had prolonged CSP latencies (P = 0.018) and shortened CSP durations (P < 0.001). The sensitivity of the CSP duration was 32.6%, and the specificity was 96.7%. The expiration-to-inspiration ratios and amplitudes of the sympathetic skin responses in the lower extremities were also reduced. Our findings indicate that the diagnostic utility of CSPs was higher than that of the autonomic tests to support the clinically suspected diagnosis of SFN. Muscle Nerve 43: 317-323, 2011
dc.identifier.doi10.1002/mus.21877
dc.identifier.eissn1097-4598
dc.identifier.issn0148-639X
dc.identifier.pubmed21321948
dc.identifier.urihttps://hdl.handle.net/11424/230230
dc.identifier.wosWOS:000287785600002
dc.language.isoeng
dc.publisherWILEY
dc.relation.ispartofMUSCLE & NERVE
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectautonomic tests
dc.subjectcutaneous silent period duration
dc.subjectdiabetes mellitus
dc.subjectinterneuron
dc.subjectsmall-fiber neuropathy
dc.subjectSMALL-FIBER NEUROPATHY
dc.subjectSYMPATHETIC SKIN-RESPONSE
dc.subjectSUDOMOTOR
dc.subjectCRITERIA
dc.subjectPROFILE
dc.subjectPLANTAR
dc.subjectBIOPSY
dc.titleASSESSMENT OF SYMPTOMATIC DIABETIC PATIENTS WITH NORMAL NERVE CONDUCTION STUDIES: UTILITY OF CUTANEOUS SILENT PERIODS AND AUTONOMIC TESTS
dc.typearticle
dspace.entity.typePublication
local.avesis.id08a9c340-a2cb-4838-b052-4a90ca5b9c13
local.import.packageSS17
local.indexed.atWOS
local.indexed.atSCOPUS
local.indexed.atPUBMED
local.journal.numberofpages7
oaire.citation.endPage323
oaire.citation.issue3
oaire.citation.startPage317
oaire.citation.titleMUSCLE & NERVE
oaire.citation.volume43
relation.isAuthorOfPublication3978eebd-304b-4af3-930c-2db9759c860d
relation.isAuthorOfPublication.latestForDiscovery3978eebd-304b-4af3-930c-2db9759c860d

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