Publication: Serum thymidine kinase 1 levels correlates with FDG uptake and prognosis in patients with non small cell lung cancer
| dc.contributor.authors | Korkmaz, Taner; Seber, Selcuk; Okutur, Kerem; Basaran, Gul; Yumuk, Fulden; Dane, Faysal; Ones, Tunc; Polat, Ozge; Madenci, Ozlem Cakir; Demir, Gokhan; Turhal, N. Serdar | |
| dc.date.accessioned | 2022-03-12T18:10:49Z | |
| dc.date.accessioned | 2026-01-10T19:19:47Z | |
| dc.date.available | 2022-03-12T18:10:49Z | |
| dc.date.issued | 2013 | |
| dc.description.abstract | Context: TK1 found to be elevated biomarker in many solid cancers. Objectives: The study aimed to assess the prognostic significance of a serum TK1 in patients with metastatic NSCLC. Methods: The study included 48 consecutive patients, newly diagnosed with metastatic NSCLC, and 10 healthy volunteers. Serum TK1 activity determined by ELISA method. Results: Patients with a bTK1 level > 156 Du L-1 had significantly shorter survival. TK1 level showed a strong correlation with primary tumor SUVmax. Discussion and conclusion: The magnitude of maximum fluorodeoxyglucose uptake in primary tumors and the serum TK1 level in patients with metastatic NSCLC were found to be independent prognostic predictors of overall survival. | |
| dc.identifier.doi | 10.3109/1354750X.2012.738250 | |
| dc.identifier.eissn | 1366-5804 | |
| dc.identifier.issn | 1354-750X | |
| dc.identifier.pubmed | 23116493 | |
| dc.identifier.uri | https://hdl.handle.net/11424/231407 | |
| dc.identifier.wos | WOS:000313677400011 | |
| dc.language.iso | eng | |
| dc.publisher | TAYLOR & FRANCIS LTD | |
| dc.relation.ispartof | BIOMARKERS | |
| dc.rights | info:eu-repo/semantics/closedAccess | |
| dc.subject | Thymidine kinase 1(TK1) | |
| dc.subject | non small cell lung cancer | |
| dc.subject | DG uptake | |
| dc.subject | prognosis | |
| dc.subject | BREAST-CANCER | |
| dc.subject | MARKER | |
| dc.subject | PROLIFERATION | |
| dc.subject | ASSOCIATION | |
| dc.subject | DEGRADATION | |
| dc.subject | RECURRENCE | |
| dc.subject | LYMPHOMA | |
| dc.subject | SURGERY | |
| dc.subject | RISK | |
| dc.title | Serum thymidine kinase 1 levels correlates with FDG uptake and prognosis in patients with non small cell lung cancer | |
| dc.type | article | |
| dspace.entity.type | Publication | |
| oaire.citation.endPage | 94 | |
| oaire.citation.issue | 1 | |
| oaire.citation.startPage | 88 | |
| oaire.citation.title | BIOMARKERS | |
| oaire.citation.volume | 18 |