Publication:
Sıçanlarda whey proteini ile oluşturulan glutatyon önkoþullandırmasının karaciğer sıcak iskemi/reperfüzyon hasarında hem oksijenaz-1 sistemi üzerine etkisi

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dc.contributor.authorGÜLLÜOĞLU, MAHMUT BAHADIR
dc.contributor.authorÇELİKEL, ÇİĞDEM
dc.contributor.authorsManukyan M. N., Yavuz Y., Erbarut I., Ogunc A. V., Ataizi-Celikel Ç., Yalcin A. S., GÜLLÜOĞLU M. B.
dc.date.accessioned2023-01-23T06:25:09Z
dc.date.accessioned2026-01-11T17:28:04Z
dc.date.available2023-01-23T06:25:09Z
dc.date.issued2008-09-01
dc.description.abstractPurpose: Oxygen radicals which are produced during reperfusion phase play a central role for hepatocellular damage during ischemia/reperfusion (I/R) injury. Antioxidant strategies appear a promising approach to prevent I/R injury. In the present study, the effect of glutathione (GSH) preconditioning established by whey protein feeding on hepatocellular injury markers was assessed in a rat hepatic normothermic I/R injury model. The interaction between intracellular GSH content and heme oxygenase-1 (HO-1) enzyme expression was also determined in order to understand the level of upgrading of HO-1 system in a high GSH content environment after preconditioning.
dc.identifier.citationManukyan M. N., Yavuz Y., Erbarut I., Ogunc A. V., Ataizi-Celikel Ç., Yalcin A. S., GÜLLÜOĞLU M. B., "The effect of glutathione preconditioning on heme oxygenase-1 system established by whey protein feeding on hepatocellular injury in a rat hepatic normothermic i/r injury model", TURKISH JOURNAL OF SURGERY, cilt.24, sa.3, ss.137-144, 2008
dc.identifier.endpage144
dc.identifier.issn2564-6850
dc.identifier.issue3
dc.identifier.startpage137
dc.identifier.urihttps://hdl.handle.net/11424/285673
dc.identifier.volume24
dc.language.isotur
dc.relation.ispartofTURKISH JOURNAL OF SURGERY
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectTıp
dc.subjectCerrahi Tıp Bilimleri
dc.subjectSağlık Bilimleri
dc.subjectMedicine
dc.subjectSurgery Medicine Sciences
dc.subjectHealth Sciences
dc.subjectCERRAHİ
dc.subjectKlinik Tıp
dc.subjectKlinik Tıp (MED)
dc.subjectSURGERY
dc.subjectCLINICAL MEDICINE
dc.subjectClinical Medicine (MED)
dc.subjectCerrahi
dc.subjectSurgery
dc.subjectLiver
dc.subjectischemia/reperfusion
dc.subjectwhey
dc.subjectglutathione
dc.subjectheme oxygenase-1
dc.titleSıçanlarda whey proteini ile oluşturulan glutatyon önkoþullandırmasının karaciğer sıcak iskemi/reperfüzyon hasarında hem oksijenaz-1 sistemi üzerine etkisi
dc.title.alternativeThe effect of glutathione preconditioning on heme oxygenase-1 system established by whey protein feeding on hepatocellular injury in a rat hepatic normothermic i/r injury model
dc.typearticle
dspace.entity.typePublication

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