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Investigation of the Relationship between Anxiety Disorder and Time Perception with DRD2 rs1800497 Polymorphism

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dc.contributor.authorULUCAN, KORKUT
dc.contributor.authorTACAL ASLAN, BESTE
dc.contributor.authorsSan H. O. , Tarlacı S., Ulucan K., Polat T., Yılmaz Ö. Ö. , Tacal Aslan B.
dc.date.accessioned2022-10-31T17:44:22Z
dc.date.available2022-10-31T17:44:22Z
dc.date.issued2022-10-01
dc.description.abstractWe have many biological systems that regulate the perception of time, which is one of our most essential abilities that allows subjectively predicting, perceiving and understanding the duration of experiences, feelings and achievements. There are findings obtained from many studies aiming to illuminate the place and importance of time, which was the most critical reference point for human understanding of life in the past, for us mammals. According to these findings, it is observed that there is a similar mechanism that provides the perception of time in almost every living organism. Time perception is vital for the healthy functioning of cognitive activities, physiological needs and behavioral relations, and the bio-psycho-social order's systematicity. Among the studies conducted, the findings obtained in the studies related to the effect of psychiatric disorders on the perception of time are somewhat blurry compared to the others. The research for this study was based on six basic Polymorphisms known to affect time perception and internal clock mechanisms. These are as follows: SLC6A4 / 5-HTTLPR, 5HT2A / T102C, DRD2 / TAQ1A, SLC6A3 / 3UTR VNTR, COMT / VAL158MET, GABRB2 A/C, CLOCK. In our study, the relationship between the rs1800497 polymorphism, which is one of these seven polymorphisms that are effective in the functioning of the internal clock in the human brain, and the inventory used in the measurement of anxiety, was examined in 14 participants. Beck Anxiety Inventory (BAI) was used to measure anxiety, and PCR was used to detect genetic variants. When the findings were evaluated, no significant relationship was found between anxiety and DRD2 rs1800497 polymorphism.
dc.identifier.citationSan H. O. , Tarlacı S., Ulucan K., Polat T., Yılmaz Ö. Ö. , Tacal Aslan B., "Investigation of the Relationship between Anxiety Disorder and Time Perception with DRD2 rs1800497 Polymorphism", journal of neurophilosophy, cilt.1, sa.2, ss.171-180, 2022
dc.identifier.doi10.5281/zenodo.7253914
dc.identifier.endpage180
dc.identifier.issn1307-6531
dc.identifier.issue2
dc.identifier.startpage171
dc.identifier.urihttps://www.jneurophilosophy.com/index.php/jnp
dc.identifier.urihttps://hdl.handle.net/11424/282728
dc.identifier.volume1
dc.language.isoeng
dc.relation.ispartofjournal of neurophilosophy
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectSağlık Bilimleri
dc.subjectHealth Sciences
dc.subjectKlinik Tıp (MED)
dc.subjectClinical Medicine (MED)
dc.subjecttime perception
dc.subjectinternal clock
dc.subjectretrospective time
dc.subjectprospective time
dc.subjectanxiety
dc.titleInvestigation of the Relationship between Anxiety Disorder and Time Perception with DRD2 rs1800497 Polymorphism
dc.typearticle
dspace.entity.typePublication
local.avesis.id75c7a0a8-a2f7-4741-9d25-956273d992d8
relation.isAuthorOfPublication46774657-48cb-4f47-a639-64e428a49411
relation.isAuthorOfPublication96dd1549-83eb-48bc-940d-a1aa5dc3b748
relation.isAuthorOfPublication.latestForDiscovery46774657-48cb-4f47-a639-64e428a49411

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