Publication: The association of osteopenia with levels of serum 25-hydroxyvitamin D and HOMA-IR values
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Date
2014
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TAYLOR & FRANCIS LTD
Abstract
Objective To determine the association of osteopenia with levels of serum 25-hydroxyvitamin D and HOMA-IR values in postmenopausal women. Methods One hundred healthy postmenopausal women were included in a cross-sectional study. Venous blood was collected after an overnight fast and 25-hydroxyvitamin D, glucose and insulin levels were measured. HOMA-IR was calculated. Bone mineral density was measured with a dual X-ray absorptiometer. Results There was no difference in serum 25-hydroxyvitamin D levels and HOMA-IR values between the two groups. A weak positive correlation between serum 25-hydroxyvitamin D levels and osteopenia was detected. Insulin resistance had a weak negative association with osteopenia. Conclusions The correlations between osteopenia and serum 25-hydroxyvitamin D levels and HOMA-IR values were weak among early postmenopausal women.
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Keywords
POSTMENOPAUSE, 25-HYDROXYVITAMIN D, HOMA-IR, INSULIN RESISTANCE, VITAMIN-D SUPPLEMENTATION, IMPAIRED GLUCOSE-TOLERANCE, BONE-MINERAL DENSITY, D DEFICIENCY, INSULIN-SECRETION, HYPOVITAMINOSIS-D, WOMEN, FRACTURE, CALCIUM, RISK